September 2, 2021

The Impact of Viral Infection on Microglia and the Aging of the Brain

A growing school of thought sees persistent viral infection as an important contributing factor in age-related neurodegeneration. The widely varying burden of infection that is present in the population could help to explain the puzzling epidemiology of conditions such as Alzheimer's disease, in that only some of the people with […]
September 1, 2021

Researchers use CERN technology to evaluate risk of COVID-19 transmission

The CERN-developed COVID Airborne Risk Assessment tool (CARA) is helping researchers from the University of Geneva assess the effectiveness of different measures to limit SARS-CoV-2 aerosol transmission in schools. Having good safety measures at schools is very important as children start going back to the classroom. But which measures are […]
September 1, 2021

A Reduced Memory B Cell Population in Older People Impairs Immune Response

The age-related decline of the immune system is complex. There are many facets to the issues of increased systemic inflammation and reduced immune competence. Here, researchers show that a necessary population of memory B cells is reduced with age, and this impairs the ability of the immune system to respond […]
August 31, 2021

Human Mini-Lungs Grown in Lab Dishes are Closest Yet to Real Thing

Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short; attempts to grow adult human lungs have historically failed because not all of the cell types survived. Undaunted, stem […]
August 31, 2021

What Makes Blood Vessels Leaky: New Insights for Sepsis Therapeutics

Sepsis occurs when the body works so hard to fight an infection that the over-activated immune system harms a patient’s own tissues as collateral damage. As a result, blood vessels can become leaky and major organs can’t get the oxygen and nutrients they require to sustain life. Sepsis is a […]
August 31, 2021

Stem cell therapy restores injured tendons to full health in study on sheep

Tendon injuries in sheep that were treated with stem cell grafts achieved, in just two months, a diameter and hardness similar to the original healthy tendon, according to the results of a study released in STEM CELLS Translational Medicine (SCTM). These findings suggest that the treatment, which uses autologous adipose […]
August 30, 2021

Researchers develop and trial new class of immunotherapy drug to fight cancer

Immunotherapy works by stimulating the body’s natural defence system to attack cancer. Currently, all antibody drugs used for cancer belong to an antibody type called IgG, but this new drug – called MOv18 IgE – is designed as an IgE type antibody. The reasoning behind the decision to study this […]