General

Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short; attempts to grow adult human lungs have historically failed because not all of the cell types survived. Undaunted, stem […]

Sepsis occurs when the body works so hard to fight an infection that the over-activated immune system harms a patient’s own tissues as collateral damage. As a result, blood vessels can become leaky and major organs can’t get the oxygen and nutrients they require to sustain life. Sepsis is a […]

Tendon injuries in sheep that were treated with stem cell grafts achieved, in just two months, a diameter and hardness similar to the original healthy tendon, according to the results of a study released in STEM CELLS Translational Medicine (SCTM). These findings suggest that the treatment, which uses autologous adipose […]

Scientists from Queen Mary University of London and UCL have shown that fetal membranes are able to heal after injury in a new study published in Scientific Reports. The integrity of the fetal membranes that surround the baby in the womb during pregnancy is vital for normal development. But fetal […]

Immunotherapy works by stimulating the body’s natural defence system to attack cancer. Currently, all antibody drugs used for cancer belong to an antibody type called IgG, but this new drug – called MOv18 IgE – is designed as an IgE type antibody. The reasoning behind the decision to study this […]

Most of what to my eyes are less promising lines of research into the treatment of aging are focused on manipulation of cellular metabolism. These approaches, such as targeting the mTOR pathway, largely derive from the study of calorie restriction and the cellular response to stress that is brought on […]

Deep learning methods help researchers to predict cancer subtypes or disease progression estimation. However, existing models process an entire set of genes. A recent study on arXiv.org proposes to take advancements in natural language processing and generate a dynamic representation of features from self-attention-based architectures. The approach emphasizes only the […]

Throughout development, life and the processes of aging, all human cells accumulate mutations, resulting in what is called mosaicism, a condition in which different cells in the same person have different DNA sequences or genetic makeup. Mosaicism occurs in every human but is mostly unnoticeable. If abnormal cells begin to […]

Why we sleep, and the processes behind sleep, are amongst the most interesting questions in modern neuroscience. Researchers at the University of Oxford have now uncovered a new target for sleep investigations within the mammalian brain – the cerebral cortex. The paper was published in Nature Neuroscience. The cerebral cortex […]

Bioengineers at the University of California San Diego have developed a cancer immunotherapy that pairs ultrasound with cancer-killing immune cells to destroy malignant tumors while sparing normal tissue. The new experimental therapy significantly slowed down the growth of solid cancerous tumors in mice. The team, led by the labs of […]