August 21, 2021

TRIM28 Inhibits Alternative Lengthening of Telomeres

Telomeres are caps of repeated DNA sequences at the ends of chromosomes. A little of the telomere length is lost with each cell division. A somatic cell with short telomeres ceases replication, and usually self-destructs. All cancers must thus continually lengthen telomeres in order to engage in unfettered replication and […]
August 20, 2021

Light can trigger key signaling pathway for embryonic development, cancer

Blue light is illuminating new understanding of a key signaling pathway in embryo development, tissue maintenance and cancer genesis. Researchers at the University of Illinois Urbana-Champaign developed an approach using blue light to activate the Wnt (pronounced “wint”) signaling pathway in frog embryos. The pathway plays a wide variety of […]
August 20, 2021

Red blood cell alterations contribute to lupus

The autoimmune disease lupus may be triggered by a defective process in the development of red blood cells (RBCs), according to a study led by researchers at Weill Cornell Medicine. The discovery could lead to new methods for classifying and treating patients with this disease. The researchers, who published their […]
August 17, 2021

Insilico Medicine announces the preclinical candidate for kidney fibrosis

Insilico Medicine announces the preclinical candidate for kidney fibrosis discovered using end-to-end artificial intelligence engine. Insilico Medicine, a global company specializing in the applications of the next-generation machine learning technologies for drug discovery and development, announced today that its AI-powered drug discovery platform had delivered the preclinical candidate (“PCC”) for […]