June 3, 2021

Ultrasound Technology Developed at U-M now in Clinical Trials for Liver Cancer

The University of Michigan is one of eight sites around the country that will enroll patients in a clinical trial to evaluate the safety and efficacy of a technology that uses ultrasound to treat liver tumors. The #HOPE4LIVER trial will employ the noninvasive technique to mechanically destroy primary and metastatic liver tumors. […]
June 3, 2021

How HIV infection shrinks the brain’s white matter

It’s long been known that people living with HIV experience a loss of white matter in their brains. As opposed to grey matter, which is composed of the cell bodies of neurons, white matter is made up of a fatty substance called myelin that coats neurons, offering protection and helping […]
June 3, 2021

Why are you gaining weight after losing it?

A lot of people are trying to lose some weight. Some just want to look better for the summer, others are fighting for better health and well-being. Losing weight is not easy and many people find themselves gaining weight soon after losing it. What makes it difficult to maintain a […]
June 3, 2021

Recent Research Sheds Light on Link Between Meningiomas and Seizures

Meningiomas are the most common type of primary brain tumor. Found in the meninges– or the tissue that surrounds the brain and spinal cord, meningiomas are often benign. However, some can behave more aggressively and recur. These tumors can affect critical neurovascular structures, such as arteries and cranial nerves, impacting […]
June 3, 2021

Scientists found a way to reduce scarring

While some people find it unsightly, scarring is actually quite an interesting thing. Scar tissue is harder and more resilient and its formation is one of the body’s natural functions. However, scars can also be quite uncomfortable or even painful. Now scientists at the University of Queensland have found a […]
June 3, 2021

Advanced Photon Source helps reveal how antibodies bind a molecule linked to cancer

Researchers have developed antibodies that can bind to phosphohistidine, an unstable molecule that’s linked to cancer. To learn how the two bind together, the team turned to the powerful X-rays at Argonne’s Advanced Photon Source. Scientists are harnessing hard X-rays in the fight against cancer. A team of researchers, in […]
June 2, 2021

New light-activated drug acts like a Trojan horse to kill cancer cells

The goal of modern cancer treatments is to kill off cancer cells while causing the least amount of damage to the surrounding tissue. This is not easy to do with current therapies, which often cause significant side effects. Now researchers at the University of Edinburgh have tested new light-activated drugs […]
June 2, 2021

Head injury and concussion in toddlers: early detection of symptoms is vital

A research team led by scientists at Université de Montréal has developed a unique observational tool for assessing children up to 5 years of age who have had a concussion. The work is explained in a study published in the Journal of Head Trauma Rehabilitation. Pediatric traumatic brain injury (TBI) is particularly […]
June 2, 2021

Low on Antibodies, Blood Cancer Patients Can Fight off COVID-19 with T Cells

Antibodies aren’t the only immune cells needed to fight off COVID-19 — T cells are equally important and can step up to do the job when antibodies are depleted, suggests a new Penn Medicine study of blood cancer patients with COVID-19 published in Nature Medicine. The researchers found that blood cancer patients with COVID-19 […]
June 2, 2021

Cholesterol-carrying protein found to help suppress immune response in pancreatic tumor microenvironment

A protein involved in cholesterol metabolism plays a previously unknown role in suppressing the body’s natural immune defenders in and around pancreatic tumours, research led by the University of Michigan Rogel Cancer Center finds. ApoE, an apolipoprotein known to play roles in cardiovascular disease and Alzheimer’s, is elevated in the blood of people […]
June 2, 2021

Improved detection of atrial fibrillation through new devices could prevent a significant number of disabling strokes

A clinical trial examining the efficacy of two devices to monitor and detect atrial fibrillation (AF), or an irregular heartbeat, in ischemic stroke patients—one an implantable device that monitors over 12 months, the other an external device that monitors over a 30-day period—found the implantable device is more than three […]
June 2, 2021

Early bird or night owl? Study links shift worker sleep to ‘chronotype’

Getting enough sleep can be a real challenge for shift workers affecting their overall health. But what role does being an early bird or night owl play in getting good rest? Researchers from McGill University find a link between chronotype and the amount of sleep shift workers can get with […]
June 1, 2021

The consequences of malnutrition are inheritable

Infant malnutrition damages the composition of intestinal bacteria, the microbiome. It has life-long consequences on the physical and intellectual development of affected children. Using pigs and mice models, Professor Bernard Henrissat from DTU Bioengineering in collaboration with the Washington University School of Medicine (USA), shows that damage to the microbiome […]
June 1, 2021

Memory, learning and decision-making studied in worms

As anyone who has ever procrastinated knows, remembering that you need to do something and acting on that knowledge are two different things. To understand how learning changes nerve cells and leads to different behaviors, researchers studied the much simpler nervous system of worms. “In this study, we can now […]
June 1, 2021

Common vaccine protects against more HPV viruses than previously known

The human papillomavirus (HPV) can cause cancer and many countries run national vaccination programmes to minimise the risk. Studies involving researchers at German Cancer Research Center, Karolinska Institutet and Tampere University now report on the longitudinal effect of common HPV vaccines. The results, which are published in The Journal of […]
May 31, 2021

Sleep-Related Breathing Disorders

We all need sleep to properly function and live. Not getting enough sleep harms our well-being, health, and immunity. Even one sleepless night can affect our bodies. Today's times do not have a positive effect on proper sleep and its sufficient amount. Work-related stress, irregular lifestyle, overwhelming responsibilities, or mental […]
May 31, 2021

Roots of major depression revealed in all its genetic complexity

A massive genome-wide association study (GWAS) of genetic and health records of 1.2 million people from four separate data banks has identified 178 gene variants linked to major depression, a disorder that will affect one of every five people during their lifetimes. The results of the study, led by the U.S. Department […]
May 31, 2021

AI innovation will make thyroid ultrasounds faster and easier

A University of Alberta spinoff company has received FDA approval for an artificial intelligence tool that could revolutionize thyroid ultrasounds, making the procedure faster and easier for thousands of Canadians who undergo it each year. MEDO.ai, with offices in Edmonton and Singapore, received approval last month from the U.S. Food […]
May 31, 2021

Delaying lung cancer surgery associated with higher risk of recurrence, death

Swiftness is essential when treating lung cancer, the second most common type of cancer in the U.S. and the country’s leading cause of cancer deaths. For patients with early-stage non-small cell lung cancer, surgical removal of a tumour-infested lung or of a smaller lung section may be the only treatment […]
May 31, 2021

Kidney chip studies trek again to Space Station

Miniaturized chips containing live, human kidney cells will be on board the scheduled June 3 Space X cargo supply Mission 22 to the International Space Station.  Inside the 3D chips, the cells are kept alive in a tiny system that delivers fluids dynamically.  These tissue chips model responses that take […]
May 31, 2021

Biologists construct a ‘periodic table’ for cell nuclei

Project to classify nuclei across the tree of life discovers how to transmute them from one type into another. One hundred fifty years ago, Dmitri Mendeleev created the periodic table, a system for classifying atoms based on the properties of their nuclei. This week, a team of biologists studying the tree of life […]
May 31, 2021

A deep dive into the brain

Researchers from ETH Zurich and University of Zurich have developed a new microscopy technique that lights up the brain with high resolution imagery. This allows neuroscientists to study brain functions and ailments more closely and non-​invasively. The way the human brain works remains, to a great extent, a topic of […]
May 30, 2021

Research Uncovers How ‘Non-professional’ Cells Can Trigger Immune Response

Worm cells sense changes in metabolism to activate defensive measures against pathogens. Included in the vast fallout stemming from the COVID-19 pandemic, scientists are paying closer attention to microbial infections and how life forms defend against attacks from pathogens. Research led by University of California San Diego scientists has shed […]
May 30, 2021

Switching off heart protein could protect against heart failure

Switching off a heart muscle protein could provide a new way for drugs to combat heart failure in people who’ve had a heart attack, according to research led by the University of Cambridge and published in the journal Nature. There is an unmet need to find drugs that can successfully improve […]
May 30, 2021

AI technique detects cancer ‘drivers,’ ‘passengers’

Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease. Now, a team led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center (NYGC) has developed a machine learning technique for detecting other modifications to DNA that have a […]
May 30, 2021

Solving the Peroxisome Puzzle

The ability to make membrane-bound organelles is a defining characteristic of eukaryotic cells — cells that constitute the bodies of all animals, plants and fungi on Earth. Membranes create enclosures that provide specialized environments for certain structures and their functions, such as the nuclei that store genetic information, or the […]