April 25, 2021

Researchers investigate the environment’s role in brain health

It’s common knowledge that our surroundings affect our health — decades of research have linked things like air, water and soil quality to various measures of physical well-being. But much less is known about how the environment changes our brain. Now, a research team at the Keck School of Medicine […]
April 25, 2021

Research shows how a sugary diet early in life could mean memory trouble later

New research shows how drinking sugary beverages early in life may lead to impaired memory in adulthood. The study, published in Translational Psychiatry, also is the first to show how a specific change to the gut microbiome — the bacteria and other microorganisms growing in the stomach and intestines — can […]
April 25, 2021

Do our brains age faster than the rest of our bodies?

If you feel your brain power diminishing as you advance into middle age and beyond, blame your neural stem cells. In a study published in Cell Stem Cell, a team led by USC Stem Cell scientist Michael Bonaguidi demonstrates that neural stem cells—the stem cells of the nervous system—age rapidly. “There is chronological […]
April 25, 2021

ERC Advanced Grant to understand enzyme stability

A new ERC project aims to improve our understanding of enzyme stability and broaden the field of potential applications for biocatalysis. Professor John Woodley from DTU Chemical Engineering has received an Advanced Grant from ERC, the European Research Council. The grant of EUR 2.4 M will for the next five […]
April 25, 2021

Computer model fosters potential improvements to ‘bionic eye’ technology

There are millions of people who face the loss of their eyesight from degenerative eye diseases. The genetic disorder retinitis pigmentosa alone affects 1 in 4,000 people worldwide. Today, there is technology available to offer partial eyesight to people with that syndrome. The Argus II, the world’s first retinal prosthesis, […]
April 25, 2021

Immunotherapy Alone Extended Life for Metastatic Lung Cancer Patients with KRAS Mutation

Real-world evidence is suggesting, for the first time, the most beneficial treatment courses that could help extend the lives of patients with metastatic non-small cell lung cancer, according to research from the Abramson Cancer Center at the University of Pennsylvania. In a new study published online in JAMA Oncology, researchers show that […]
April 25, 2021

Targeting Cell Maintenance Processes to Improve Mitochondrial Function and Slow Aging

Many approaches shown to slow aging in animal studies involve an increased efficiency of cell maintenance processes such as the ubiquitin-proteasome system and various types of autophagy. Here researchers discuss the improvement of autophagy in order to slow the age-related decline of mitochondrial function. Mitochondria are the power plants of […]
April 24, 2021

International research teams explore genetic effects of Chernobyl radiation

In two landmark studies, researchers have used cutting-edge genomic tools to investigate the potential health effects of exposure to ionizing radiation, a known carcinogen, from the 1986 accident at the Chernobyl nuclear power plant in northern Ukraine. One study found no evidence that radiation exposure to parents resulted in new […]
April 23, 2021

Computer-based image analysis of atherosclerosis in the carotid artery opens up opportunities for better stroke prevention and individualized treatment

Patients with atherosclerosis today usually receive preventive treatment only after a heart attack or stroke because diagnostic methods that can identify individuals and atherosclerotic plaques with high risk are lacking. In addition, the choice of treatment, both surgical and medical, is based on large patient studies and the possibilities for […]
April 23, 2021

21st century medical needles for high-tech cancer diagnostics

The diagnosis of diseases like cancer almost always needs a biopsy – a procedure where a clinician removes a piece of suspect tissue from the body to examine it, typically under a microscope. Many areas of diagnostic medicine, especially cancer management, have seen huge advances in technology, with genetic sequencing, […]
April 23, 2021

Scientists cast new understanding of how skin repairs itself

University of Manchester scientists have cast new light on how our skin repairs itself, bringing the possibility of regeneration of the organ a step closer. The study team, funded by the Medical Research Council and Helmut Horten Foundation, showed the activation of specific parts of the DNA leading to better division of human skin cells. […]
April 23, 2021

Vitamin D deficiency may impair muscle function

New research has uncovered a possible link between vitamin D deficiency and impaired muscle function, which could help older adults better maintain muscle strength as they age. A study led by Dr Andrew Philp from the Garvan Institute of Medical Research, recently published in the Journal of Endocrinology, used experimental models to […]
April 23, 2021

Does the Gut Microbiome Contribute to Age-Related Anabolic Resistance

The gut microbiome is a highly varied collection of microbial populations that acts in symbiosis with the body to process food and provide needed metabolites. With age, there is a detrimental shift in these populations. Those generating useful metabolites, such as butyrate, diminish in number. Those capable of infiltrating tissue, […]
April 22, 2021

Zooming in on muscle cells

An international team, led by Stefan Raunser, Director at the Max Planck Institute of Molecular Physiology in Dortmund, in collaboration with Mathias Gautel at the King's College in London, has produced the first high-resolution 3D image of the sarcomere, the basic contractile unit of skeletal and heart muscle cells, by […]
April 22, 2021

Cell-based method for the regeneration of myelin

Myelin is tremendously important for the correct and rapid transmission of electrical signals in the brain. This lipid-rich membrane, which wraps axons, is damaged in certain degenerative nerve disorders. Most of these are rare hereditary diseases with serious clinical courses. Generation of induced oligodendrocyte progenitor cells (iOPCs) from somatic fibroblasts […]
April 22, 2021

Targeted therapies thanks to biomedical informatics

The new “LOOP Zurich – Medical Research Center” promotes patient-focused therapies – for example in oncology and neuro-rehabilitation. To achieve its goals, the centre brings together specialist knowledge in the fields of biomedicine, clinical research and bioinformatics from the University of Zurich, ETH Zurich as well as Zurich’s four university […]
April 22, 2021

Toward safer stem cell transplants

For cancer patients, the use of hematopoietic stem cell transplants can be a game-changer in terms of treatment and recovery. However, most people need to undergo a combination of chemotherapy and radiation before transplants become an option. A new article in Chemical & Engineering News, the weekly newsmagazine of the […]
April 22, 2021

Scientists find new point of access for targeting eating disorders and obesity

Scientists have identified a potential drug target for treating obesity and eating disorders such as anorexia nervosa, a condition for which no therapeutics are currently available. In a new study scheduled to publish in Science Translational Medicine, a team of researchers from the University of Michigan and Vanderbilt University pinpoints […]
April 22, 2021

For Scleroderma, Algorithm Helps Better Screen for Fatal Complication

Screening for a sometimes fatal condition among patients with a rare autoimmune disease could soon – thanks to a computer algorithm – become even more accurate. Researchers at Michigan Medicine found that an internet application improved their ability to spot pulmonary arterial hypertension in patients with systemic sclerosis, or scleroderma. […]
April 22, 2021

Optical technology from TAU can make an immediate melanoma diagnosis

An innovative optical technology that can distinguish between different types of skin cancer melanoma has been developed in the laboratory of Professor Abraham Katzir of the Raymond and Beverly Sackler Faculty of Exact Sciences at Tel Aviv University. The method, which is rapid, non-invasive, and painless, was tried successfully on about one hundred patients […]
April 22, 2021

Researchers identify proteins that cause intestinal disease

Researchers from Tel Aviv University (TAU) have created an artificial intelligence platform that can identify the specific proteins that allow bacteria to infect the intestines. The platform paves the way for the creation of smart drugs that can neutralize the proteins and prevent disease, eliminating the use of antibiotics. Participating in the […]
April 22, 2021

Micro-molded ‘ice cube tray’ scaffold is next step in returning sight to injured retinas

Tens of millions of people worldwide are affected by diseases like macular degeneration or have had accidents that permanently damage the light-sensitive photoreceptors within their retinas that enable vision. The human body is not capable of regenerating those photoreceptors, but new advances by medical researchers and engineers at the University […]
April 22, 2021

FSU researcher awarded $2.2M NIH grant to study impact of Alzheimer’s disease on sleep-related brain function

A Florida State University researcher has been awarded a $2.2 million grant from the National Institutes of Health to study sleep-related brain function in Alzheimer’s disease, a progressive disorder that affects memory and behaviour in millions of Americans. Assistant Professor of Psychology and Neuroscience Aaron Wilber will receive the grant, awarded […]