January 10, 2023

How does multicellularity develop?

The unicellular marine organism Salpingoeca rosetta belongs to the group of choanoflagellates. When hunting for bacteria, these protozoa can detect their prey by means of certain signaling molecules. They then form rosette-like multicellular structures to better catch their prey. However, some bacteria produce inhibitors to prevent the formation of the […]
January 9, 2023

Self-assembling proteins can store cellular “memories”

Using these engineered proteins, researchers can record histories that reveal when certain genes are activated or how cells respond to a drug. As cells perform their everyday functions, they turn on a variety of genes and cellular pathways. MIT engineers have now coaxed cells to inscribe the history of these […]
January 8, 2023

Study reveals previously unknown function of immune cells

Certain T cells can secrete cytokines that are normally part of the innate immune system, as researchers from the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI) and an international research team discovered. They have thus revealed several previously unknown properties of these immune cells that are relevant […]
January 8, 2023

Telling Left From Right: Cilia as Cellular Force Sensors During Embryogenesis

Although the human body is externally symmetric across the left-right axis, there are remarkable left-right asymmetries in the shape and positioning of most internal organs including the heart, lungs, liver, stomach, and brain. Left-right asymmetry is known to be established during early embryogenesis by a small cluster of cells termed […]