December 4, 2021

The Continued Quest for Pluripotent Adult Stem Cells

Does the adult mammalian body contain naturally pluripotent stem cells, capable for forming any other cell type, given the right stimuli? Over the past twenty years various groups have argued that it does, but none of those scientists have produced evidence that is both compelling and easily replicated. If they […]
December 3, 2021

Microglia as Mediators of the Link Between Psychological Stress and Cognitive Aging

Psychological stress appears to modestly accelerate some measures of aging, though most of the evidence for this correlation comes from animal studies. Evidence points to chronic inflammation, and the immune system in general, as an important factor in this correlation. Separately, chronic inflammation in brain tissue is known to be important in neurodegenerative conditions, and […]
December 3, 2021

Nuclear deformation research could advance artificial tissue engineering

Biomedical Engineering Professor Corey Neu and Benjamin Seelbinder wanted to answer two fundamental questions. How do cells adapt to their environment and how does a mechanical environment influence a cell? What they discovered during their more than six years of research has the potential to tackle major health obstacles and advance […]
December 2, 2021

On the Ability of Redundant Blood Vessels to Lower Cardiovascular Mortality

A few strategies offer the possibility of growing additional redundant blood vessels, though this is far from rigorously proven. Intermittently provoking hematopoietic stem cells to leave the bone marrow via CXCL12 upregulation, for example. Humans are not completely uniform in their major blood vessel networks, there are variant populations with […]
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