October 21, 2019

“Back in Time”: Researchers Unravel the Early Makings of an Exhausted T Cell

The immune system struggles to defeat cancer or chronic infections because many of the T cells that leap into action end up “exhausted,” rendering them ineffective against disease. That path to exhaustion and what triggers it is a crucial one that researchers aim to better understand so they can stop […]
October 21, 2019

Embryo’s early development revealed in a dish

During embryonic development, the entire nervous system, the skin and the sensory organs emerge from a single sheet of cells known as the ectoderm. While there have been extensive studies of how this sheet forms all these derivatives, it hasn’t been possible to study the process in humans – until now. […]
October 19, 2019

Research Identifies Proteins Responsible for Cancer Spreading

Advances in the sciences have made it easier than ever to live with and survive various kinds of cancer. One of the lingering challenges that remains is metastasis, or the ability of cancer cells to migrate to new pathological sites within the host’s body. October is National Breast Cancer Awareness […]
October 18, 2019

Study shows why even well-controlled epilepsy can disrupt thinking

Transient bursts of high-frequency electrical activity in epileptic brain tissue can impair cognition even when no seizure is occurring, Stanford scientists have found. A study by Stanford University School of Medicine investigators may help explain why even people benefiting from medications for their epilepsy often continue to experience bouts of difficulty thinking, […]
October 18, 2019

Children exposed to Swedish snus during pregnancy have higher blood pressure

Children are more likely to have higher systolic blood pressure by age six if their mom used the Swedish powdered tobacco product snus during pregnancy. This according to a new study by researchers at Karolinska Institutet published in the Journal of the American Heart Association. “Tobacco products of any type […]
October 18, 2019

Scientists link hormone production in baby wallabies to how some human girls are born with genitalia that appear more male than female

Research led by the Universities of Birmingham and Manchester has made a connection between the way baby wallabies produce male hormones and how some human girls are born with genitalia that resembles those of a boy. The research, published in PNAS and supported by the Wellcome Trust, Medical Research Council, shows that […]
October 18, 2019

New Player in Human Aging

A new character has stepped onstage in the story of human aging: neural excitation. The brain’s neural activity, long implicated in disorders ranging from dementia to epilepsy, plays a role in human aging and life span, according to research led by scientists in the Blavatnik Institute at Harvard Medical School. The […]
October 18, 2019

Frontotemporal lobar degeneration consortium combines and continues research efforts

A new National Institutes of Health grant merges two ongoing frontotemporal lobar degeneration (FTLD) studies to form a new, integrated consortium. FTLD is a rare disease that can affect parts of the brain responsible for personality, behavior, language, and motor function. The funding, from NIH’s National Institute on Aging (NIA) […]
October 18, 2019

NIH scientists develop test for uncommon brain diseases

National Institutes of Health scientists have developed an ultrasensitive new test to detect abnormal forms of the protein tau associated with uncommon types of neurodegenerative diseases called tauopathies. As they describe in Acta Neuropathologica, this advance gives them hope of using cerebrospinal fluid, or CSF—an accessible patient sample—to diagnose these and […]
October 18, 2019

Exercise may reduce risk of cancer recurrence and improve survival rates

Exercise might lower the risk of cancer recurrence and improve survival rates, according to the latest guidelines released today about exercise and cancer. “There's some provocative data coming out that says patients who exercise during and after treatment might actually even lower their risk of the disease coming back, which […]
October 18, 2019

Algorithm Personalizes Which Cancer Mutations Are Best Targets for Immunotherapy

As tumor cells multiply, they often spawn tens of thousands of genetic mutations. Figuring out which ones are the most promising to target with immunotherapy is like finding a few needles in a haystack. Now a new model developed by researchers in the Abramson Cancer Center at the University of Pennsylvania hand-picks […]
October 17, 2019

Scientists discover skin keeps time independent of the brain

Squids, octopuses, cuttlefish, amphibians, and chameleon lizards are among the animals that can change the color of their skin in a blink of an eye.  They have photoreceptors in their skin that operate independently of their brains. The photoreceptors are part of a family of proteins known as opsins. Mammals […]
October 17, 2019

Cell family trees tracked to discover their role in tissue scarring and liver disease

Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions. The research by academics from the Universities of Edinburgh and Bristol and funded by the Wellcome Trust and Medical Research Council is published in Nature Communications. […]
October 17, 2019

Weight-loss surgery cuts risk of major birth defects

Children born to women who underwent gastric bypass surgery before becoming pregnant had a lower risk of major birth defects than children born to women who had severe obesity at the start of their pregnancy. That’s according to a matched cohort study by researchers at Karolinska Institutet and Örebro University […]
October 17, 2019

Increased performance in female athletes after testosterone supplementation

Researchers at Karolinska Institutet and the Swedish School of Sport and Health Sciences have investigated the effects of testosterone supplementation in young athletically active women in a randomized, placebo-controlled trial. The results, which are published in the British Journal of Sports Medicine, show that there is a causal relationship between […]
October 17, 2019

Study focuses on repair and reversal of damage caused by Huntington's disease

UCLA research identifies a potential strategy that may lead to treatment for the disorder. A new study examining the role that star-shaped brain cells called astrocytes play in Huntington’s disease has identified a potential strategy that may halt the disease and repair some of the damage it causes. Astrocytes interact […]
October 16, 2019

Deaf infants more attuned to parent’s visual cues, study shows

Eye gaze helps infants communicate. Through everyday interactions, eye gaze establishes a social connection between parent and child and is linked to early word learning. But can learn experiences before a baby’s first birthday prompt babies to pay more attention to their parent’s eye gaze? To test this, a research […]
October 16, 2019

New drug shows promise as immune therapy for cancer

A therapy developed by Yale researchers stimulates immune cells to shrink or kill tumors in mice, according to a new study published in the Journal of Experimental Medicine. The therapy is effective alone or in combination with existing cancer immunotherapies, and it appears to have lasting effects, the researchers said. The […]
October 16, 2019

Yale scientists help immune system find hidden cancer cells

Cancer cells are masters at avoiding detection, but a new system developed by Yale scientists can make them stand out from the crowd and help the immune system spot and eliminate tumors that other forms of immunotherapies might miss, the researchers report in the journal Nature Immunology. The new system […]
October 16, 2019

Synthetic cells make long-distance calls

The search for effective biological tools is a marathon, not a sprint, even when the distances are on the microscale. A discovery at Rice University on how engineered communities of cells communicate is a long step in the right direction. The Rice lab of synthetic biologist Matthew Bennett has designed […]
October 15, 2019

Drug-Light Combo Could Offer Control Over CAR T-Cell Therapy

Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control. They developed a system that allows them to select where and when CAR T cells get turned on so that they destroy cancer cells without harming […]
October 15, 2019

Sperm and egg cell ‘immune response’ protects koala DNA

Discovery of a type of immunity that protects koalas’ DNA from viruses has importance for the survival of koalas and our fundamental understanding of evolution. A team of scientists from The University of Queensland and University of Massachusetts Medical School are studying tissue samples from koalas to understand how a […]
October 15, 2019

More interventions needed for mothers as prenatal stress could affect baby's brain, say researchers

New research from King’s College London has found that maternal stress before and during pregnancy could affect a baby’s brain development. In their study published in Biological Psychiatry, MRC Doctoral Researcher in Perinatal Imaging and Health, Alexandra Lautarescu and Head of Advanced Neuroimaging, Professor Serena Counsell, for the first time looked at the relationship between […]
October 15, 2019

Unique immune cell could help stop breast cancer

A unique type of immune cell has been discovered in human breast tissue, and breast cancer patients with more of these cells are more likely to survive, finds new research from the King's College London and the Francis Crick Institute. The study, published in Science Translational Medicine and led by Professor Adrian Hayday, […]
October 15, 2019

New research center to explore muscle health and disease

A new, interdisciplinary muscle research center is celebrating its opening at its main location at UW Medicine South Lake Union. With collaborating labs across the University of Washington campus and at other Seattle-area institutions and beyond, the Center for Translational Muscle Research will encompass a myriad of muscle science and […]