September 2, 2019

A fruitful endeavor: Researcher examines berry polyphenols as potential treatment for cardiovascular treatment

A Florida State University researcher is examining how the polyphenol compounds found in blackberries could be used to help fight the buildup of artery plaque. Gloria Salazar, associate professor of nutrition, has received $805,409 from the James and Esther King Biomedical Research Program at the Florida Department of Health to […]
August 30, 2019

Low cost mobile technology shifts the dial on cardiovascular risk in rural Indonesia

An Australian-developed mobile app supported system that helps health systems identify and better manage people at high risk of cardiovascular disease has been shown to improve the use of appropriate medications and lower blood pressure in rural Indonesian communities. The study, published in JAMA Cardiology, showed that 15% of high […]
August 30, 2019

Artificial red blood cells enable research into malaria invasion

Researchers at the University of Bristol and Imperial College London have established a new model system that uses red blood cells grown in the laboratory to study how malaria parasites invade red blood cells. The work, which was funded by the National Institute for Health Research and NHS Blood and Transplant and is published in […]
August 30, 2019

An Apple a Day

Achieving or maintaining a healthy body weight is one key to preventing cardiovascular disease. But even experts don’t agree on the best way to achieve that goal, with some recommending eliminating carbohydrates and others emphasizing reducing fats to lose weight. Few studies have investigated the effects of these specific macronutrients […]
August 30, 2019

U of A researchers discover new biomarker for rare autoimmune disease

University of Alberta researchers identified a unique biological marker that can be used to identify the presence of the rare autoimmune disease myasthenia gravis, predict the course of the disease and identify new, personalized treatments. In a study published in the journal Metabolomics, neurologist Zaeem Siddiqi, graduate student Derrick Blackmore and their […]
August 29, 2019

What we don't know about prenatal opioid exposure

Pregnancy can be a time of anxious uncertainty, particularly if there are any risks of complications. The question always arises, from parents, grandparents, friends and others: “Will the baby be OK?” In cases where the baby has been exposed to opioids in the womb, the answer is unclear. As part […]
August 29, 2019

Polycystic Kidney Disease: Strike Three

For people with polycystic kidney disease (PKD), life can be a never-ending cycle of symptoms: aches and pains, abdominal swelling, kidney stones, high blood pressure. The disease frequently leads, at worst, to a suite of major issues, including kidney failure, cysts in the liver and vascular problems, including strokes. PKD is a […]
August 29, 2019

Remodeling unhealthful gut microbiomes to fight disease

You are what you eat — right down to the microbiome living in your gut. Diet can affect which microbes are in the intestinal tract, and research has shown that harmful gut microbiome changes can lead to illnesses such as heart disease, obesity and cancer. Today, scientists will report the […]
August 29, 2019

Peptide hydrogels could help heal traumatic brain injuries

Traumatic brain injury (TBI) –– defined as a bump, blow or jolt to the head that disrupts normal brain function –– sent 2.5 million people in the U.S. to the emergency room in 2014, according to statistics from the U.S. Centers for Disease Control and Prevention. Today, researchers report a […]
August 29, 2019

Runaway Mitochondria Cause Telomere Damage in Cells

Researchers at UPMC Hillman Cancer Center provide the first concrete evidence for the long-held belief that sick mitochondria pollute the cells they’re supposed to be supplying with power. The paper, published in the Proceedings of the National Academy of Sciences, involves a causal experiment to kick off a mitochondrial chain reaction that […]
August 29, 2019

Study Suggests Exercise After Concussion Improves Recovery

After a sports-related concussion, traditional recovery recommendations have previously called for weeks or months of rest, depending on the duration of a person’s symptoms. But Michael Popovich, M.D., M.P.H., a sports neurologist at Michigan NeuroSport, thinks this method could actually do more harm than good. Recent studies have suggested that regular, daily activities during […]
August 29, 2019

Addition of growth factors to unique system helps new bone formation

The development of new bone can be a multistep process: first, stem cells differentiate into cartilage cells. Next, the cartilage cells become bone cells. But that’s not all: the cells must experience some mechanical stresses during the transformation in order to transform efficiently from stem cells to bone cells. Researchers […]
August 28, 2019

Genetic risk is associated with differences in gut microbiome

Children with a high genetic risk of developing type 1 diabetes have different gut microbiomes than children with a low risk, according to a new study. The results suggest that genetic risk can shape an individual’s response to environmental factors in the development of autoimmune diseases. Both hereditary and environmental […]
August 28, 2019

Downstream Effects

Former professional football players who have experienced concussion symptoms, including loss of consciousness, disorientation or nausea after a head injury, are more likely to report low testosterone and erectile dysfunction (ED), according to research published in JAMA Neurology. The research—based on a survey of more than 3,400 former NFL players […]
August 28, 2019

Neurological brain markers might detect risk for psychotic disorders

Help may be on the way for people who might lose contact with reality through a psychotic disorder, such as schizophrenia. People who may hear and see things that are not there could have symptoms of psychosis, better known as psychotic disorders. Now, researchers at the University of Missouri have found neurological […]
August 28, 2019

New study suggests exercise is good for the aging brain

Exercise seems to endow a wealth of benefits, from the release of happiness-inducing hormones to higher physical fitness. New research shows it may provide a boost to the mind too. University of Iowa researchers have found that a single bout of exercise improves cognitive functions and working memory in some older […]
August 28, 2019

Scientists advance search for memory’s molecular roots

A new piece of a difficult puzzle — the nature of memory — fell into place this week with a hint at how brain cells change structure when they learn something. Interactions between three moving parts — a binding protein, a structural protein and calcium — are part of the […]
August 28, 2019

Prenatal pesticide exposure linked to changes in teen’s brain activity

Organophosphates are among the most commonly used classes of pesticides in the United States, despite mounting evidence linking prenatal exposure to the chemicals to poorer cognition and behavior problems in children. A new study led by University of California, Berkeley, researchers is one of the first to use advanced brain […]
August 28, 2019

New add-on drug to treat off episodes in adults with Parkinson's disease approved by FDA

The U.S. Food and Drug Administration today approved Nourianz (istradefylline) tablets as an add-on treatment to levodopa/carbidopa in adult patients with Parkinson’s disease (PD) experiencing “off” episodes. An “off” episode is a time when a patient’s medications are not working well, causing an increase in PD symptoms, such as tremor […]
August 27, 2019

Genetic redundancy aids competition among symbiotic bacteria in squid

The molecular mechanism used by many bacteria to kill neighboring cells has redundancy built into its genetic makeup, which could allow for the mechanism to be expressed in different environments, say researchers at Penn State and the University of Wisconsin-Madison. A paper online in the Journal of Bacteriology provides insights into the molecular mechanisms of competition […]
August 26, 2019

Low levels of dietary vitamins linked to frailty in older adults

Researchers from The Irish Longitudinal Study on Ageing (TILDA) at Trinity College have shown in the largest study to date that lower levels of specific dietary vitamins and antioxidants are associated with frailty. Their findings have been published in the prestigious Journal of American Medical Directors Association. Frailty is a common chronic […]
August 26, 2019

Fish oil supplements have no effect on Type 2 diabetes

Omega-3 fats have little or no effect on risk of Type 2 diabetes according to new research from the University of East Anglia. Increased consumption of omega 3 fats is widely promoted globally because of a common belief that it will protect against, or even reverse, conditions such as diabetes. […]
August 26, 2019

Research shows human cells assembling into fractal-like clusters

Tree-like branching structures are everywhere in the human body, from the bronchial system in the lungs to the spidering capillaries that supply blood to the extremities. Researchers have long worked to understand the cellular signaling needed to build these intricate structures, but new research suggests that simple physics may play […]
August 26, 2019

How our genes and environment influence BMI and height

Environmental conditions influence our body mass index (BMI) by increasing or decreasing the effect of inherited genetic variations, University of Queenslandresearchers have discovered. A team led by Huanwei Wang and Professor Jian Yang from UQ’s Institute for Molecular Bioscience found the opposite for human height – that the genetic effects that influence it are very stable […]
August 26, 2019

Cell suicide could hold key for brain health and food security

Research into the self-destruction of cells in humans and plants could lead to treatments for neurodegenerative brain diseases and the development of disease-resistant plants. A study co-led by The University of Queensland’s Professor Bostjan Kobe identified the role certain proteins play in cellular suicide. “To sustain life, diverse organisms like humans and […]
August 26, 2019

Compound hastens sexual maturity, and death, in worms

Every day, people are exposed to myriad chemicals both natural and synthetic, some of which may affect human physical development. Testing them has proven challenging, but researchers from Boyce Thompson Institute have come up with a way. Using Caenorhabditis elegans (C. elegans), a soil roundworm, the researchers have shown that […]