June 25, 2019

Low-carb diet may reduce diabetes risk independent of weight loss

A low-carb diet may have benefits for people at risk of developing type 2 diabetes even if they don’t lose any weight, a new study suggests. Researchers at The Ohio State University wanted to know what happens to obese people with metabolic syndrome, a precursor to diabetes, when they eat […]
June 23, 2019

Being overweight now will cause you great trouble when you're 50

Make a choice today – become healthier. Move more, eat better, drink plenty of water and lose weight. There is a number of reasons why you should do that, including health risks associated with being overweight. Scientists from UCL found that people who are obese from childhood through to middle […]
June 21, 2019

Cancer is smarter than you think: Q&A with Geeta Mehta

Geeta Mehta studies cancer not simply as masses of cells but as structured organs with multiple cell types that communicate with each other and interact with the body—much like your lungs or liver. “Tumors are not merely cancerous cells that undergo mindless proliferation. Rather, they are highly organized and interconnected organ […]
June 21, 2019

Swell Snapshots

After decades of attempts by the scientific community, researchers at Harvard Medical School and Peking University have provided the first clear look at a protein implicated in a vast array of inflammatory conditions. The finding, published in Nature, lifts a blindfold that has hampered scientists' ability to intervene when the […]
June 21, 2019

Screen Time and the Brain

Whether we like it or not, digital devices are everywhere. Some of us can barely put them down, even when we’re with cherished family and friends. While these devices can enhance learning and build community, they can also interfere with everything from sleep to creativity. Pediatrician Michael Rich, wants to […]
June 21, 2019

New findings can help Parkinson's patients

For patients with Parkinson’s disease, early signs of a certain part of the brain being broken down has been shown to have a negative impact on the course of the disease. The results of a study which researchers from Aarhus University and Aarhus University Hospital are behind can potentially alter […]
June 21, 2019

Signature of an ineffective immune response to cancer revealed

Our immune system is programmed to destroy cancer cells. Sometimes it has trouble slowing disease progression because it doesn’t act quickly or strongly enough. In a study published in The Journal of Clinical Investigation, researchers from the University of Montreal Hospital Research Centre (CRCHUM) revealed the genetic signature of this […]
June 21, 2019

Targeting the Microbiome Could Improve Parkinson’s Therapy

For some people with Parkinson’s disease, Levodopa is a wonder drug, capable of eliminating almost overnight the tremors and movement difficulties that characterize the neurodegenerative disorder. Other patients are not so lucky – the drug is either much less effective, or its power seems to wane after just a few […]
June 21, 2019

Landmark study signals shift in thinking about stem cell differentiation

A pioneering new study led by Florida State University biologists could fundamentally change our understanding of how embryonic stem cells differentiate into specific cell types. The research, published in the journal Stem Cell Reports, calls into question decades of scientific consensus about the behavior of embryonic stem cells as they […]
June 20, 2019

Study of multiethnic genomes identifies 27 genetic variants associated with certain diseases

In a study published in the journal Nature, researchers identified 27 new genomic variants associated with conditions such as blood pressure, type 2 diabetes, cigarette use and chronic kidney disease in diverse populations. The team collected data from 49,839 African-American, Hispanic/Latino, Asian, Native Hawaiian, Native American and people who identified […]
June 20, 2019

New toolkit guides health-care professionals to assess dementia in a new way

University of Alberta-led research is revolutionizing the way health professionals assess the decision-making capacity of seniors in Edmonton and across the province. The model led to a 60 per cent drop in referrals to geriatricians and an 80 per cent drop in the number of capacity interviews required when it […]
June 20, 2019

Excessive Napping Linked to Cognitive Decline in Older Men

Excessive napping may be an early warning sign of age-related cognitive decline in older men, according to a 12-year study by UC San Francisco scientists. The researchers used wrist-mounted sensors to track sleep–wake habits over five days in nearly 3,000 men over the age of 65 living in community housing […]
June 20, 2019

Oregon State researchers identify compounds that starve melanoma cancer cells of energy

Researchers at Oregon State University and Oregon Health & Science University have found a possible counterpunch to the drug resistance of melanoma, the most dangerous form of skin cancer. The findings, published in the journal Molecular Carcinogenesis, are important because in the United States alone, almost 100,000 new melanoma cases will […]
June 20, 2019

Scientists chart course toward a new world of synthetic biology

Genetically engineered trees that provide fire-resistant lumber for homes. Modified organs that won’t be rejected. Synthetic microbes that monitor your gut to detect invading disease organisms and kill them before you get sick. These are just some of the exciting advances likely to emerge from the 20-year-old field of engineering […]
June 19, 2019

Using gene editing, neuroscientists develop a new model for autism

Using the genome-editing system CRISPR, researchers at MIT and in China have engineered macaque monkeys to express a gene mutation linked to autism and other neurodevelopmental disorders in humans. These monkeys show some behavioral traits and brain connectivity patterns similar to those seen in humans with these conditions. Mouse studies […]
June 19, 2019

Blood Test Predicts Stroke Risk in Patients with Diabetes

Having diabetes is a risk factor for many other health conditions, including stroke. “Every 40 seconds an American has a stroke,” says Frederick Korley, M.D., Ph.D., an assistant professor of emergency medicine at Michigan Medicine. “To be successful at preventing strokes from occurring, we first need to accurately identify those who […]
June 19, 2019

Gut Bacteria from Breastfeeding Linked to Improved Infant Response to Vaccines

Higher levels of a customary gut bacteria enhanced by breastfeeding in early infancy were found to be coupled with an improved response to vaccines in infants through two years of age, according to a first-of-its-kind study by Agricultural Research Service (ARS) scientists and their colleagues. Infants in the study, who […]
June 19, 2019

New clues on tissue damage identified in rheumatoid arthritis and lupus

Research supported by the Accelerating Medicines Partnership (AMP) on Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) provides new insights into tissue damage for these autoimmune conditions. Findings include the identification of novel molecular signatures related to immune system signaling in kidney cells that may reflect their active role in disease process; […]
June 19, 2019

How to Reinvigorate Exhausted Immune Cells and Stop Cancer Along the Way

The human immune system relies on a delicate balance of finely tuned cell types that keep germs and cancerous cells in check. In cancer and chronic infections this balance can be disrupted, resulting in immune system dysfunction or “exhaustion.” An important protein called TOX, which varies in amount in different […]
June 19, 2019

On the Pulse

It is likely that in the not-distant future wounds will heal faster with the help of an electrical pulse that promotes rapid cell growth. The same type of pulse may be used for more efficient and effective delivery of drugs to fight disease. Such treatments rely on a process known […]
June 19, 2019

How common gut bacteria trigger a lethal autoimmune disease

What causes the immune system, designed to protect us, to turn on the body and attack healthy cells? Common bacteria that reside in the human gut may be partly to blame, say Yale researchers, who studied the origins of a serious autoimmune disease that frequently affects young women. For their […]
June 19, 2019

Special fibroblasts help pancreatic cancer cells evade immune detection

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the world. Mostly chemoresistant, PDAC so far has no effective treatment. Understanding the connective tissue, called stroma, that surrounds, nurtures, and even protects PDAC tumors, is key to developing effective therapeutics. “PDAC patients are diagnosed really late, so […]
June 19, 2019

Anti-inflammation approach shows promise for preventing cancer metastasis

An anti-inflammatory drug called ketorolac, given before surgery, can promote long-term survival in animal models of cancer metastasis, a team of scientists has found. Furthermore, so-called “pro-resolution” therapies can also trigger the immune system to eliminate metastatic cells. The research also suggests that flanking chemotherapy with anti-inflammatory drugs can unleash […]
June 19, 2019

Rutgers Scientist Creates “Virtual Biopsy” Device to Detect Skin Tumors

Using sound vibrations and pulses of near-infrared light, a Rutgers University scientist has developed a new “virtual biopsy” device that can quickly determine a skin lesion’s depth and potential malignancy without using a scalpel. The ability to analyze a skin tumor non-invasively could make biopsies much less risky and distressing […]
June 19, 2019

Cancer vaccine on its way? Scientists confirm nan­o­vac­cines are safe, well tol­er­ated and effective

Immunotherapy is going to be the next big thing in cancer treatment. Someday cancer will be stopped at its tracks by drugs that could be essentially called vaccines. Scientists at the University of Helsinki developed porous silicon and adenovirus-based biohybrid nanovaccines that are safe, well tol­er­ated, and effective. Immunotherapy is […]