June 18, 2019

Waking up early increases the risk of death, but not for everyone

Our modern world is moving at an incredible pace. This means that we also have to hustle. Many people are waking up with a sound of an alarm clock, sometimes incredibly early. But is it healthy? Scientists from UCL conducted a study looking at sleep and mortality from across different […]
June 18, 2019

Deleting Old Cells

New research from Harvard Medical School researchers at Joslin Diabetes Center has shown that insulin resistance in mice increases the proportion of dysfunctional aged beta cells. Such an increase in aged beta cells could lead to type 2 diabetes. The researchers then confirmed a similarly increased proportion of aged beta […]
June 18, 2019

Immune system can slow degenerative eye disease, NIH-led mouse study shows

A new study shows that the complement system, part of the innate immune system, plays a protective role to slow retinal degeneration in a mouse model of retinitis pigmentosa, an inherited eye disease. This surprising discovery contradicts previous studies of other eye diseases suggesting that the complement system worsens retinal […]
June 18, 2019

Aging delayed in older mice given blood component from young mice

New research has identified a novel approach to staving off the detrimental effects of aging, according to a study from Washington University School of Medicine in St. Louis. The study suggests that a protein that is abundant in the blood of young mice plays a vital role in keeping mice […]
June 17, 2019

Study seeks to expand treatment options for rare airway disease

Armed with $1.2 million in funding from the National Heart, Lung and Blood Institute (NHLBI), researchers at Vanderbilt University Medical Center are searching to understand the cause of a rare airway disease in hopes of developing better treatments. Idiopathic subglottic stenosis (iSGS) is an unexplained narrowing of the windpipe just […]
June 17, 2019

VR slow training for a future without falls

An elderly woman balances on one leg while watching a television display. What do you think she’s doing? She’s actually in the midst of using virtual reality (VR) technology for slow training. While Japan is leading the world in terms of a superaging society, the problem is the big gap […]
June 17, 2019

Altered brain activity in antisocial girls – new study

Teenage girls with severe antisocial behaviour display reduced brain activity and weaker connectivity between the brain regions implicated in emotion regulation, according to a new study involving researchers from the University's Department of Psychology. The findings, published in the journal Biological Psychiatry, offer a neurobiological explanation for the difficulties some girls […]
June 17, 2019

Researchers’ discovery could lead to improved therapies for Duchenne muscular dystrophy

A new multi-institution study spearheaded by researchers at Florida State University and the University of California, Los Angeles suggests a tiny protein could play a major role in combating heart failure related to Duchenne muscular dystrophy (DMD), the most common lethal genetic disorder among children. In collaboration with scientists from […]
June 14, 2019

Causal association between excess body fat and cardiovascular disease

Using a method called Mendelian randomisation, researchers at Karolinska Institutet show that there is a causal association between high BMI and several heart and blood vessel diseases, especially if the fat mass is high. The greatest risk increase was observed for a condition known as aortic valve stenosis. The study […]
June 14, 2019

Rheumatoid arthritic pain could be caused by antibodies

Antibodies that exist in the joints before the onset of rheumatoid arthritis can cause pain even in the absence of arthritis, researchers from Karolinska Institutet in Sweden report. The researchers believe that the finding, which is published in the Journal of Experimental Medicine, can represent a general mechanism in autoimmunity […]
June 14, 2019

Scientists Slow Progression of Debilitating Neurodegenerative Disorder

An international study led by scientists in Oakland, Calif., and Munich, Germany, may offer hope to children and adults with a rare and debilitating genetic disorder, Pantothenate Kinase-associated neurodegeneration (PKAN), as well as a potentially new approach to treat other neurodegenerative disorders, such as Alzheimer’s, Parkinson’s disease and multiple sclerosis. […]
June 14, 2019

Any which way: Flies go all-in to overcome defect, reach adulthood

New research from the University of Nebraska-Lincoln has revealed how fruit fly larvae with a seemingly fatal flaw can survive and advance to adulthood. As in all multicellular organisms, both the nuclei and mitochondria of fruit fly cells contain distinct DNA. Those two genomes include complementary instruction manuals for collectively […]
June 13, 2019

Get them moving before kindergarten

Physical activity in early childhood may have an impact on cardiovascular health later in life, according to new research from McMaster, where scientists followed the activity levels of hundreds of preschoolers over a period of years. They found that physical activity in children as young as three years old benefits […]
June 13, 2019

New Discovery could Rewrite Textbooks on Evolutionary Theory

With the publication of a new study in the leading scientific journal Nature, a group of researchers from the University of Queensland may have overturned the way scientists think of the evolution of animals on Earth. Thanks to advanced technology, the group was able to make an intuitive, yet unexpected […]
June 13, 2019

A homing beacon for chemotherapy drugs

Killing tumor cells while sparing their normal counterparts is a central challenge of cancer chemotherapy. If scientists could put a “homing beacon” in tumors, they could attract these medicines and reduce side effects caused by the drugs acting on healthy cells. Now, researchers have made a hydrogel that, when injected […]
June 13, 2019

NIH-developed technique prevents obstruction in heart valve replacement

A novel technique has proven successful in preventing coronary artery obstruction during transcatheter aortic valve replacement (TAVR), a rare but often fatal complication. Called Bioprosthetic Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery obstruction (BASILICA), the technique will increase treatment options for high-risk patients who need heart valve procedures. […]
June 13, 2019

A microscopic topographic map of cellular function

A decade of research leads MU scientists to a better understanding of how materials move out of cells. The flow of traffic through our nation’s highways and byways is meticulously mapped and studied, but less is known about how materials in cells travel. Now, a team of researchers at the University […]
June 13, 2019

Immunotherapy Drug Shows Potential to Cure Advanced Lung Cancer

In a new study including Yale Cancer Center and Smilow Cancer Hospital researchers, the cancer immunotherapy drug pembrolizumab (Keytruda), increased survival for patients with advanced non-small cell lung cancer (NSCLC), a disease once considered an aggressive, and uniformly fatal cancer. The findings were presented at the American Society of Clinical […]
June 13, 2019

Study: unhealthy gut promotes spread of breast cancer

An unhealthy, inflamed gut causes breast cancer to become much more invasive and spread more quickly to other parts of the body, new research from the University of Virginia Cancer Center suggests. Melanie Rutkowski, a research faculty member in UVA’s Department of Microbiology, Immunology and Cancer Biology, found that disrupting the […]
June 12, 2019

New gene-editing system precisely inserts large DNA sequences into cellular DNA

Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology. A team led by researchers from Broad Institute of MIT and Harvard, and the McGovern Institute for Brain Research at MIT, has characterized and engineered a new gene-editing system that can precisely and […]
June 12, 2019

Cause of hardening of the arteries – and potential treatment – identified

A team of UK scientists have identified the mechanism behind hardening of the arteries, and shown in animal studies that a generic medication normally used to treat acne could be an effective treatment for the condition. The team, led by the University of Cambridge and King’s College London, found that […]
June 12, 2019

Gene mutations are pointing towards the root causes of the multiple sclerosis

Multiple sclerosis is a disease, which is characterized by the insulating covers of nerve cells in the brain and spinal cord. There is no cure and existing treatments can have tremendous side effects. Eventually MS leads to disability. Now an international team of scientists led by the University of British […]
June 12, 2019

Global study links better education, wealth to improved heart health

Findings from a sweeping global study conducted by SFU Health Sciences professor Scott Lear, among others, reveal a direct correlation between socioeconomic status and one’s susceptibility to heart attacks and strokes. Lear, who holds the Pfizer/Heart & Stroke Foundation Chair in Cardiovascular Prevention Research at St. Paul’s Hospital, is the […]
June 12, 2019

Younger women who suffer a heart attack are almost always smokers

Smoking is the overriding cause of heart attacks for people between the ages of 30 and 50, and register-based studies from Aarhus University and Aarhus University Hospital can now contribute with figures and ratios: Three out of four younger patients with a major heart attack are smokers – and for […]
June 12, 2019

The goal is personalised medicine for patients with schizophrenia

No more trial and error: If things go as Professor Søren Dinesen Østergaard and his new Postdoc Fredrik Hieronymus hope, patients with schizophrenia will be treated using personalised medicine in the not so distant future. The research project is supported by the Lundbeck Foundation to the tune of DKK 1.6 […]