May 28, 2019

A newly discovered mechanism reveals how Parkinson’s disease can spread

Tiny channels between nerve cells are involved in a newly discovered mechanism of how Parkinson’s disease can spread throughout the brain. Researchers from LiU demonstrate that harmful protein aggregates can “hitch a lift” with channel-forming proteins, and in this way spread to healthy cells. Neurodegenerative diseases, such as Alzheimer’s, Parkinson’s […]
May 28, 2019

New method for analyzing genes activity helps predict cancer patients survival

An international research team developed a new method for determining cell types in a tissue sample. The scientists determined the link between the activity of genes in the same cell type and made a model capable of “recognizing” different cell types in mixed samples based on this relation. This approach […]
May 28, 2019

A new molecule to boost modern cancer therapies

Highly effective modern cancer therapies rely on immune cells to attack and shrink tumours. Medicine instructs body’s immune system to attack cancer cells, which is a safer approach, but scientists from the University of Edinburgh found a way to boost this effect. They found a molecule that boosts the function […]
May 28, 2019

A step closer to identifying cause of a blinding disease

Leber hereditary optic neuropathy (LHON) is an inherited form of vision loss that causes people to have trouble with their colour vision and difficulty seeing in the centre of their visual field. Due to the founder effect from the filles du roi, there is a disproportionate preponderance of a particular LHON mutation among […]
May 28, 2019

Synthetic E. coli pushes the limits of gene synthesis

Designing and building organisms from scratch could be the Holy Grail of synthetic biology. It therefore comes as no surprise that genome synthesis works get a lot of attention and are celebrated as high profile works form the community. In 2016 J. Craig Venter Institute scientists reported the synthesis of […]
May 27, 2019

How Learning and Decision-Making Share a Common Underlying Brain Mechanism

In a pair of recently published papers, researchers at Carnegie Mellon University, along with local and international collaborators, shed light on how specific circuits in the brain can simultaneously make decisions and learn from their outcomes. Consider eating brunch at your favorite restaurant: How do you know whether the eggs […]
May 27, 2019

Artificial Intelligence system spots lung cancer before radiologists

Deep learning — a form of artificial intelligence — was able to detect malignant lung nodules on low-dose chest computed tomography (LDCT) scans with a performance meeting or exceeding that of expert radiologists, reports a new study from Google and Northwestern Medicine. This deep-learning system provides an automated image evaluation […]
May 27, 2019

Hypertension Found in Children Exposed to Flower Pesticides

In a study published in the journal Environmental Research, researchers at University of California San Diego School of Medicine found higher blood pressure and pesticide exposures in children associated with a heightened pesticide spraying period around the Mother’s Day flower harvest. This study involved boys and girls living near flower […]
May 27, 2019

Scientists are developing nano-submarines for drug delivery

Treating diseases on cellular level is extremely difficult because of the microscopic scale. It is especially true for cancer, which is why contemporary therapies are affecting a lot of the surrounding tissue. However, chemical and biomedical engineers from the UNSW Sydney proved that it is possible to design effective miniscule […]
May 27, 2019

Trial of potential new treatment for type 1 diabetes

Researchers at Cardiff and Swansea Universities are running a new trial to investigate whether a medicine currently used for the skin condition psoriasis could also be used to help people with type 1 diabetes produce some of their own insulin. Over 300,000 people in the UK have Type 1 diabetes […]
May 27, 2019

Proton Therapy Lowers Risk of Side-Effects Compared to Conventional Radiation

Cancer patients getting proton therapy instead of traditional photon radiation are at a significantly lower risk of experiencing side-effects from their radiation therapy, while cure rates are almost identical between the two groups. Researchers in the Perelman School of Medicine at the University of Pennsylvania conducted the largest review of its […]
May 27, 2019

Mobile App With Activity Tracker Promotes Physical Activity in Women

A mobile phone app designed to promote physical activity, combined with an activity tracker and brief personal counseling, was effective in encouraging women to exercise for three months and to continue their activity for six more months after their app use ended, according to a study by researchers at UC […]
May 27, 2019

Researcher wants to unlock the mysteries of strabismus

Strabismus, also known as being cross-eyed or having a wandering eye, is one of the most common reasons that children undergo eye surgery. But little has changed in its treatment since the 1800s, according to Jolene Rudell, acting assistant professor of ophthalmology at the University of Washington School of Medicine. […]
May 27, 2019

How a zebrafish could help solve the mysteries of genetic brain disease

A close look at the rapidly developing zebrafish embryo is helping neuroscientists better understand the potential underpinnings of brain disorders, including autism and schizophrenia. Researchers at The Ohio State University were interested in understanding changes in neurological development that arise from a genetic defect associated with neurological disease – specifically, […]
May 27, 2019

Mapping bone-marrow microenvironment sheds fresh light on leukaemia

Stem cells are surrounded and protected by the stem-cell niche – the microenvironment – of the tissue in which they are found. Researchers at Karolinska Institutet have mapped the stem-cell niche in the bone marrow of mice and studied how it is influenced by developing leukemia. Their results, which are […]
May 24, 2019

Study Explores Why Prostate Cancer Mortality is Higher in Black Men

Black men are more likely to be diagnosed with prostate cancer and nearly 2.5 times more likely to die of the disease compared to non-Hispanic white men. The question is why. Are black men more likely to carry genes that drive deadlier forms of the disease? What societal disparities might […]
May 24, 2019

Determining Risk of Diabetic Kidney Disease

Researchers ID circulating proteins involved in progression of diabetic kidney disease. In a breakthrough study published in Nature Medicine, Harvard Medical School researchers at Joslin Diabetes Center have identified a group of 17 circulating inflammatory proteins that are consistently associated with the development and progression of diabetic kidney disease. These 17 […]
May 24, 2019

Names prompt distinct brain activity in preschoolers

A study from Penn and CHOP found that when preschoolers with autism spectrum disorder hear their name, their neural patterns match those of their typically developing peers. The finding held regardless of whether the child’s mom or a stranger called the name. Infants as young as 6 months old can […]
May 24, 2019

Study probes the powering of contractions in heart failure

Current treatments can slow progression of heart failure, but do not address the underlying issues, including specific problems that cause systolic heart failure.  In this condition, the heart doesn’t contract vigorously enough in  pushing blood into the body’s circulation. The heart muscle contractions that  pump blood are generated by interactions […]
May 23, 2019

Proton therapy for cancer lowers risk of side effects

Proton therapy results in fewer side effects than traditional X-ray radiation therapy for many cancer patients, according to a new study led by Washington University School of Medicine in St. Louis and the Perelman School of Medicine at University of Pennsylvania. Even with reduced side effects, proton therapy resulted in […]
May 23, 2019

NIH announces two awards for multi-year studies of influenza immunity in children

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has announced two awards for the study of influenza immunity in children. The awards, which may total more than $64 million over seven years, will support studies led by Cincinnati Children’s Hospital Medical Center […]
May 23, 2019

Study shows incidence rates of aggressive subtypes of uterine cancer rising

New findings from a study by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, show that U.S. incidence rates for aggressive subtypes of uterine cancer rose rapidly among women ages 30 to 79 from 2000 to 2015. The findings also reveal racial disparities, including […]
May 23, 2019

A new pathway for an anti-aging drug

In 1972, Easter Island, called Rapa Nui, famous for its moai statues, offered a new wonder: the discovery of the drug rapamycin. Over the past three decades, rapamycin, which was isolated from soil bacteria, has been applied as an immuno-suppressor in a multitude of ways, including to coat coronary stents […]
May 23, 2019

3D-printed device detects biomarkers of preterm birth

Preterm birth (PTB) — defined as birth before the 37th week of gestation — is the leading complication of pregnancy. If doctors had a simple, accurate and inexpensive way to identify women at risk for the condition, they could develop better prevention strategies. Now researchers have created a 3D-printed microchip electrophoresis device that […]
May 23, 2019

A new approach to targeting cancer cells

A University of California, Riverside, research team has come up with a new approach to targeting cancer cells that circumvents a challenge faced by currently available cancer drugs. A cancer target is often a rogue protein that signals cancer cells to proliferate uncontrollably and invade organs. Modern cancer drugs have […]
May 22, 2019

Researchers Unravel Mechanisms that Control Cell Size

Working with bacteria, a multidisciplinary team at the University of California San Diego has provided new insight into a longstanding question in science: What are the underlying mechanisms that control the size of cells? Nearly five years ago a team led by Suckjoon Jun, a biophysicist at UC San Diego, […]