January 4, 2019

The number of people living with dementia in the world doubled since 1990

Age-related dementia is a terrible debilitating condition, which affects millions around the globe. It is one of the reasons why so many of us are afraid of getting old. Scientists say that dementia is actually a growing problem – the global burden of dementia has doubled since 1990, according to […]
January 4, 2019

Metabolic syndrome patients need more vitamin C to break cycle of antioxidant depletion

A higher intake of vitamin C is crucial for metabolic syndrome patients trying to halt a potentially deadly cycle of antioxidant disruption and health-related problems, an Oregon State University researcher says. That’s important news for the estimated 35 percent of the U.S. adult population that suffers from the syndrome. “What […]
January 4, 2019

Cancer cells steer a jagged path

A jagged little protein appears to be key to how cancer stem cells differentiate and enable metastasis, according to researchers at Rice University and the Duke University School of Medicine. Rice scientists who have formed several theories on how cancer grows and spreads connected the dots for a more complete […]
January 4, 2019

Scientists are looking for a way to cut off melanoma's escape routes

Melanoma is an extremely dangerous cancer, which spreads quickly and is relatively hard to treat. One of the more effective strategies would be to stop cancer from spreading, making its presence a bit more local and, therefore, easier to treat. But how do you achieve that? Scientists from the University […]
January 4, 2019

An Errant Editing Enzyme Promotes Tumor Suppressor Loss and Leukemia Propagation

Writing in the journal Cancer Cell, researchers at University of California San Diego School of Medicine report that detection of “copy editing” by a stem cell enzyme called ADAR1, which is active in more than 20 tumor types, may provide a kind of molecular radar for early detection of malignancies and […]
January 4, 2019

Cutting off melanoma’s escape routes

Stopping melanoma from spreading to other parts of the body might be as simple as cutting off the blood supply to the cancer, according to researchers. Scientists from The University of Queensland’sDiamantina Institute have discovered stem cells which form blood vessels in tumours, and have identified how to ‘switch the cells off’. […]
January 3, 2019

Swim, Jump, Shoot, Lift: Paralympians reveal brain’s amazing ability to adapt

Professor Kimitaka Nakazawa built a career studying neurological rehabilitation after spinal cord injury. He had long been interested in sports physiology and when he moved to the University of Tokyo in 2009, he had the academic freedom to add studies of dancers and baseball pitchers to his research. It wasn't […]
January 3, 2019

Artificial Intelligence Can Detect Alzheimer’s Disease in Brain Scans Six Years Before a Diagnosis

Using a common type of brain scan, researchers programmed a machine-learning algorithm to diagnose early-stage Alzheimer’s disease about six years before a clinical diagnosis is made – potentially giving doctors a chance to intervene with treatment. No cure exists for Alzheimer’s disease, but promising drugs have emerged in recent years […]
January 3, 2019

New compound shows promise in treatment of Alzheimer’s

Yale researchers have identified a drinkable cocktail of designer molecules that interferes with a crucial first step of Alzheimer’s and even restores memories in mice, they report n the journal Cell Reports. The binding of amyloid beta peptides to prion proteins triggers a cascade of devasting events in the progression of […]
January 3, 2019

Tiny, implantable device uses light to treat bladder problems

A team of neuroscientists and engineers has developed a tiny, implantable device that has potential to help people with bladder problems bypass the need for medication or electronic stimulators. The team — from Northwestern University, Washington University in St. Louis and the University of Illinois in Urbana-Champaign — developed a […]
January 3, 2019

Sandia microneedles technique may mean quicker diagnoses of major illnesses

When people are in the early stages of an undiagnosed disease, immediate tests that lead to treatment are the best first steps. But a blood draw — usually performed by a medical professional armed with an uncomfortably large needle — might not be quickest, least painful or most effective method, […]
January 3, 2019

Caesarean sections prevent natural transfer of immune system-boosting bacteria

Baby‘s birth is always an exciting moment, but it can also be hugely stressful. In fact, in certain cases natural birth is not even an option and parents are encouraged to choose caesarean section. It is a medical procedure that can save baby‘s and mother‘s lives in certain situation. Now […]
January 2, 2019

Don’t go breaking my heart

For the first time, engineers have demonstrated an electronic device to closely monitor beating heart cells without affecting their behavior. A collaboration between the University of Tokyo, Tokyo Women’s Medical University and RIKEN in Japan produced a functional sample of heart cells with a soft nanomesh sensor in direct contact […]
December 31, 2018

Eating well and exercising improve surgical outcomes

Eating well and exercising before surgery can improve surgical outcomes in the context of standardized care pathways, even among patients who have extremely serious procedures, according to a study by UW Medicine scientists published in PLOS ONE. “I tell my patients, ‘This is your job. This is something you can do […]
December 28, 2018

Japanese AI System Differentiates between Cancer Cells and Automatically Detects Their Susceptibility to Radiotherapy

Reporting in the academic journal Cancer Research, a group of Japanese researchers have devised an artificial intelligence (AI) system (called VGG16) that can identify different types of cancer cells comprising a single tumour, and successfully gauge their susceptibility to radiotherapy. “This study demonstrates rapid and accurate identification of radioresistant tumour […]
December 28, 2018

Better mouse model built to enable precision-medicine research for Alzheimer's

Incorporating genetic diversity into a mouse model of Alzheimer’s disease resulted in greater overlap with the genetic, molecular and clinical features of this pervasive human disease, according to a study funded by the National Institute on Aging (NIA), part of the National Institutes of Health. The study also suggests that […]
December 28, 2018

Want to improve your memory? Start drawing even if you're not good at it

There is nothing fun about getting old. One of the worst things is deterioration of mental capacities, such as memory. As people get older, retention of new information typically declines, but there are ways to delay and slow down this process. Scientists from the University of Waterloo found that drawing […]
December 28, 2018

Researchers unravel mystery of how, when DNA replicates

A team of Florida State University researchers has unlocked a decades-old mystery about how a critical cellular process is regulated and what that could mean for the future study of genetics. In cells, DNA and its associated material replicate at regular intervals, a process essential to all living organisms. This […]
December 28, 2018

How do hair follicles grow? A Yale-led study untangles the science

An outstanding question in dermatology that researchers have studied for decades is: How do hair follicles emerge from a sea of seemingly uniform skin cells during embryonic development? New research findings from a Yale-led team offer answers to that question, which may lead to strategies for regenerating lost hair follicles […]
December 28, 2018

Looking ‘outside the tumor’ to detect lung cancer

Scientists in Anant Madabhushi’s computational imaging lab at Case Western Reserve University have started thinking outside the box—or in their case, looking outside the tumor. They’re hoping that this novel computerized approach represents a historic leap in diagnosing cancer using just routine CAT scans. If proven successful, it would be […]
December 27, 2018

Novel drops could prevent vision loss after eye trauma or severe infections

Eye trauma or various infections often lead to impaired vision or even blindness. However, these conditions do not have such an effect in themselves – usually disability occurs due to scar tissue forming in cornea. This outer layer of the eye is transparent, but turns opaque due to scarring. Now […]
December 27, 2018

Cell by Cell: HMS studies featured in Science's 'Breakthrough of the Year'

A series of studies conducted by teams led by Harvard Medical School systems biologists Allon Klein, Marc Kirschner and Sean Megason, as well as the work of teams led by Alexander Schier at Harvard University in collaboration with Aviv Regev at the Broad Institute of MIT-Harvard, have been featured as part of the “2018 Breakthrough of the […]
December 27, 2018

Understanding Alzheimer’s disease through collaboration and data sharing

Of the many outstanding mysteries of neuroscience, the pathogenic origins of Alzheimer’s disease (AD) remain one of the most perplexing neurological puzzles. An estimated 5.7 million Americans are presently afflicted with the disease, which gradually ravages the aging brain, resulting in progressive loss of memory followed by other cognitive abilities. […]
December 27, 2018

New insight into aggressive breast cancers

Professor Matt Smalley, from Cardiff University’s European Cancer Stem Cell Research Institute, said: “There are 150 new cases of breast cancer diagnosed in the UK every day. To achieve better outcomes for people facing this disease, we need to better understand how it develops so we can improve therapies. “We […]
December 27, 2018

Fragile X Syndrome Research Gains Momentum

With the help of a new human embryonic stem cell line, researchers make initial strides toward treatment for the genetic mutation. Fragile X syndrome is the most common inherited cause of intellectual disability and autism and poses a significant burden to affected families. The syndrome gets its name because — […]
December 27, 2018

Gene discovery reveals new targets for treating atherosclerosis, inflammatory diseases

A group of genes that has been largely ignored by scientists could play critical roles in atherosclerosis (hardening of the arteries), inflammation, and likely obesity and other metabolic diseases, new research suggests. The discovery was made by researchers at the University of Virginia School of Medicine in the context of how our bodies recognize and remove […]
December 27, 2018

Healing with words, through writing workshops for cancer patients

Jack L. Ivey learned he had cancer in 2007. Though he’d been writing since middle school, he had never penned any poetry. Then he joined the Writing a Life workshop, a program that encourages cancer patients at Penn Medicine’s Abramson Cancer Center (ACC) to express their feelings about cancer through writing. In […]