November 13, 2018

Cardiovascular disease, Alzheimer’s genetically linked

Studying DNA from more than 1.5 million people, an international team of researchers — led by Washington University School of Medicine in St. Louis and the University of California, San Francisco — has identified points of DNA that increase the risk of cardiovascular disease and also heighten the risk for […]
November 13, 2018

New gene therapy reprograms brain glial cells into neurons

A new gene therapy can turn certain brain glial cells into functioning neurons, which in turn could help repair the brain after a stroke or during neurological disorders like Alzheimer's or Parkinson’s diseases. In a series of studies in animals, a team of Penn State researchers led by Gong Chen […]
November 12, 2018

Violence in childhood leads to accelerated aging, study finds

Children who suffer abuse are more likely to age faster, while those who endure food insecurity or neglect may develop more slowly, according to new research led by the University of Washington. Violence, psychological or emotional abuse, deprivation and neglect — adverse childhood experiences — can affect both epigenetic, or […]
November 12, 2018

Key molecule responsible for learning and memory discovered

Unlike old dogs, old adults can indeed learn new tricks thanks to a protein molecule called netrin. Netrin is known to help set up the healthy nervous system in an infant’s developing brain by directing brain cells to make appropriate connections with other brain cells. New research conducted by scientists […]
November 12, 2018

Breast cancer cells become invasive by changing their identity

Researchers at Karolinska Institutet have identified a protein that determines the identity and invasive properties of breast cancer cells. The finding could lead to the development of new therapeutic and diagnostic strategies to target breast cancer invasion and metastasis. The study is published in the scientific journal Cancer Research. Cancer cell […]
November 12, 2018

Link between vaccines and allergies dismissed

Researchers at Karolinska Institutet, having compared the development of allergies in children with and without the recommended vaccinations, find no support for the claim that childhood vaccination can increase the risk of allergy. The study is published in EClinicalMedicine, a new open access journal published by The Lancet. “Even though Sweden has […]
November 12, 2018

Women who are 'larks' have a lower risk of developing breast cancer

Women who are 'larks', functioning better at the beginning of the day than the end of the day, have a lower of risk breast cancer, according to new research led by the University of Bristol presented at the 2018 NCRI Cancer Conference. The study of several hundred thousand women, which […]
November 11, 2018

Small Tissue Chips in Space a Big Leap Forward for Research

A small device that contains human cells in a 3D matrix represents a giant leap in the ability of scientists to test how those cells respond to stresses, drugs and genetic changes. About the size of a thumb drive, the devices are known as tissue chips or organs on chips. […]
November 9, 2018

New immunotherapy technique can specifically target tumor cell

A new immunotherapy screening prototype developed by University of California, Irvine researchers can quickly create individualized cancer treatments that will allow physicians to effectively target tumors without the side effects of standard cancer drugs. UCI’s Weian Zhao and Nobel laureate David Baltimore with Caltech led the research team that developed […]
November 9, 2018

Genes behind rapid deer antler growth, hardening identified

Stanford scientists and their collaborators have identified two key genes responsible for the rapid growth of deer antlers. They hope their insights will open the door to new approaches for treating bone diseases and fractures. Each spring, male deer sprout a new pair of antlers, which are essentially temporary external […]
November 9, 2018

Tiny nanostraws to deliver molecules to human cells safely and efficiently

Researchers can design the perfect molecule to edit a gene, treat cancer or guide the development of a stem cell, but none of that will matter in the end if they can’t get their molecule into the human cells they want to manipulate. The solution to that problem, described in […]
November 9, 2018

New Options and New Hope in Lung Cancer Treatment

Lung cancer is among the most frequently occurring forms of cancer, second only to prostate cancer in men and breast cancer in women. It’s also the most lethal cancer type, claiming the lives of more adults than colon, breast and prostate cancer combined. About 8 in 10 lung cancer cases […]
November 7, 2018

Predicting Risk of Major Coronary Events

Physicians can assess the risks of major coronary events in someone with diabetes reasonably well. Among those with diabetes, there are well-established indicators of risk such as weight, fasting levels of blood glucose and family history of the disease. Doctors also can consider more general measures of health such as […]
November 7, 2018

Gut bacteria may control movement

A new study puts a fresh spin on what it means to “go with your gut.” The findings, published in Nature, suggest that gut bacteria may control movement in fruit flies and identify the neurons involved in this response. The study was supported by the National Institute of Neurological Disorders […]
November 7, 2018

Breast milk, formula nurture similarities, differences in gut microbes

Infant formula is designed to mimic human breast milk not only in nutrients but also by nurturing a similar set of microbes in the digestive tract. Such microbes are indispensable in keeping us healthy: They crowd out disease-causing bacteria, influence our metabolism, and synthesize many vitamins and amino acids, the […]
November 7, 2018

New Platform Based on Biology and Nanotechnology Carries mRNA Directly to Target Cells

Delivering an effective therapeutic payload to specific target cells with few adverse effects is considered by many to be the holy grail of medical research. A new Tel Aviv University study explores a biological approach to directing nanocarriers loaded with protein “game changers” to specific cells. The groundbreaking method may prove useful […]
November 7, 2018

Neonatal Birthweights Increase in Direct Proportion to Number of Births

A new Tel Aviv University study finds that neonatal birthweights increase in direct proportion with the number of births of the mother in at least 30 percent of all cases. The study focuses on the risk of having large for gestational age (LGA) infants, babies who clock in at higher than the […]
November 6, 2018

Two apps target cancer risk in marginalized populations

Anne Teitelman believes the key to helping women stay healthy is to meet them where they are, to bring the personal, health-related care into their daily lives, not sequester it to a once- or twice-a-year visit to a nurse practitioner, doctor, or another care provider. So, the Penn Nursing researcher built two apps. The […]
November 6, 2018

Screen-time does not disrupt children's sleep, new study finds

Screens are now a fixture of modern childhood. As young people spend an increasing amount of time on electronic devices, the effects of these digital activities has become a prevalent concern among parents, caregivers, and policy-makers. Research indicating that between 50% to 90% of school-age children might not be getting […]
November 6, 2018

Bipolar structure for nerve cell migration

The cerebral cortex is responsible for a large number of complex brain functions, ranging from the perception of sensory stimuli through alertness, memory and language to consciousness. Neurobiologists at the Max Planck Institute for Experimental Medicine in Göttingen have decoded a new regulatory principle that controls the development of the […]
November 5, 2018

HHS announces $2.6 million in prizes to redesign dialysis as part of KidneyX

The U.S. Department of Health and Human Services (HHS) and the American Society of Nephrology (ASN) have committed $2,265,000 in prize money for “KidneyX: Redesign Dialysis,” a prize competition that challenges the public to develop better treatment options for patients with kidney failure. This prize competition is the first in […]
November 5, 2018

Nutrient Effect

Type 2 diabetes is driven by many metabolic pathways—some driven by amino acids, the molecular building blocks for proteins. Harvard Medical School scientists at Joslin Diabetes Center found that one amino acid, alanine, may produce a short-term lowering of glucose levels by altering energy metabolism in the cell. “Our study […]
November 2, 2018

To Ward off Fatty Liver, Breast is Best for Mom

Researchers at University of California San Diego School of Medicine and Kaiser Permanente have discovered that mothers who breastfed a child or children for six months or more are at lower risk for developing non-alcoholic fatty liver disease (NAFLD) years later during mid-life. With no other current prevention options aside […]
October 31, 2018

Old Drug, New Hope for Pediatric Brain Cancer

Some drugs for heart disease might also work against brain cancer, according to an analysis by researchers from the Jackson Laboratory (JAX), Connecticut Children’s Medical Center (CCMC), and UConn Health. The researchers used a new approach to identify five heart medicines that might also be effective at fighting the most […]