General

Scientists at the University of Cambridge have identified rare genetic variants – carried by one in 3,000 people – that have a larger impact on the risk of developing type 2 diabetes than any previously identified genetic effect. Type 2 diabetes is thought to be driven in part by inherited […]

Researchers from the Max Planck Institute for Developmental Biology in Tübingen and their collaborators describe a strain of giant kelp that is genetically male, but presents phenotypic features of females. Their findings shed light on the molecular basis of how sexual development is initiated in this species. Giant kelp can […]

In the United States, nearly every pediatric doctor’s visit begins with three measurements: weight, height and head circumference. Compared to average growth charts of children across the country, established in the 1970s, a child’s numbers can confirm typical development or provide a diagnostic baseline to assess deviations from the curve. Yet, […]

A 'perfect storm' of genetic mutations, toxic proteins and a defect in natural cell recycling has been uncovered in University of Queensland research that could lead to treatments for neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Researchers have found brain cells are particularly vulnerable to the impacts of the triple threat, […]

Researchers at The University of Queensland, working to gain a better understanding of how brain cells work, have discovered the underlying mechanism of a rare genetic mutation that can cause epilepsy. Dr Victor Anggono from UQ’s Queensland Brain Institute said his team made the ground-breaking findings while researching nerve cell communications, which are […]

Taken together, the bacteria, viruses, fungi and other microbes that live in our intestines from the gut microbiome, which plays a key role in the health of people and animals. In new research from the University of Minnesota, the University of Notre Dame and Duke University, scientists found that genetics […]

A diet rich in fermented foods enhances the diversity of gut microbes and decreases molecular signs of inflammation, according to researchers at the Stanford School of Medicine. In a clinical trial, 36 healthy adults were randomly assigned to a 10-week diet that included either fermented or high-fibre foods. The two diets […]

How much can a simple blood sample tell us about a person’s health? Can it give clues about whether a person will develop cardiovascular disease or leukemia? Can it predict how severe a person’s heart disease will be? John Dick, senior scientist at Princess Margaret Cancer Centre, University Health Network […]

A bioengineering professor at The University of Texas at Arlington is developing a technique to diagnose tiny breast tumors that could reduce the anxiety, uncertainty and high costs often faced by patients. Biopsy results show that about 80% of very small tumors are benign; 15% are low-grade, non-life-threatening cancers; and […]

In a recently published review article in Nature Reviews Endocrinology, two researchers at the Department of Physiology and Pharmacology at KI, concludes where the field of research isepige regarding causes behind and development of, Polycystic Ovary Syndrome (PCOS) and how epigenetic processes can contribute to the development of the syndrome. […]

NineSigma, on behalf of Daiichi Sankyo Co., Ltd., seeks novel drug targets or seeds, which are related to the cancer-neuron axis, an interaction between the nervous system and tumour. Recent studies suggest that the nervous system including nerve cells and neural factors exaggerates cancer cell growth in the tumour microenvironment (Trends […]

In 2020, PLOS ONE announced a Call for Papers on Modeling Cell Proliferation and the Cell Microenvironment. This week, we celebrate the launch of this collection, which includes a number of papers offering new insights into this vital topic. Understanding the cellular microenvironment and how cells proliferate has a number of useful applications, and […]