June 8, 2021

Lung cancer’s resistance to chemotherapy reveals new treatment approach

New research at the Garvan Institute of Medical Research and ANZAC Research Institute has uncovered a mechanism that helps lung cancer cells resist standard chemotherapies. A team led by Associate Professor David Croucher and Associate Professor Andrew Burgess found that individual lung adenocarcinoma cells, the most common form of lung […]
June 8, 2021

Study reveals worrying disparity in excess deaths during pandemic

A study led by researchers at the Universities of Manchester and York published in The Lancet Regional Health – Europe has revealed strong disparities in rates of excess deaths in England and Wales during the first 30 weeks of the COVID-19 pandemic. According to the research team, deaths compared with […]
June 7, 2021

New method of gene analysis prevents early death in familial hypercholesterolemia

Researchers at Karolinska Institutet have investigated how a newly developed algorithm in connection with gene analysis can be used to improve the possibilities of preventing premature vascular disease and death in individuals with the hereditary lipid disorder, familial hypercholesterolemia. The findings, published in the Journal of Internal Medicine, show how […]
June 7, 2021

Studies reveal skull as unexpected source of brain immunity

The immune system is the brain’s best frenemy. It protects the brain from infection and helps injured tissues heal, but it also causes autoimmune diseases and creates inflammation that drives neurodegeneration. Two new studies in mice suggest that the double-edged nature of the relationship between the immune system and the […]
June 7, 2021

Study shows novel test can detect new and recurrent bladder cancer

A revolutionary new urine screening test that utilizes a novel Keratin 17 (K17) cancer biomarker can detect the presence of new bladder cancer in patients with hematuria, or blood in the urine, according to a study led by researchers at Yale Cancer Center, Stony Brook University, and KDx Diagnostics, Inc. The findings also […]
June 6, 2021

“Electronic Nose” Accurately Sniffs Out Hard-to-Detect Cancers

An odor-based test that sniffs out vapors emanating from blood samples was able to distinguish between benign and pancreatic and ovarian cancer cells with up to 95 percent accuracy, according to a new study from researchers at the University of Pennsylvania and Penn’s Perelman School of Medicine. The findings suggest that the Penn-developed […]
June 6, 2021

Healing hydrogels

Hydrogels are polymer materials made mostly from water. They can be used in a wide range of medical and other applications. However, previous incarnations of the materials suffered from repeated mechanical stress and would easily become deformed. A novel crystal that can reversibly form and deform, allows hydrogels to rapidly […]
June 6, 2021

Tiny implant cures diabetes in mice without triggering immune response

A team of researchers led by diabetes specialists and biomedical engineers at Washington University School of Medicine in St. Louis and Cornell University has demonstrated that using a miniscule device, they can implant insulin-secreting cells into diabetic mice. Once implanted, the cells secrete insulin in response to blood sugar, reversing […]
June 5, 2021

A connectomic study of a petascale fragment of human cerebral cortex

The human brain is the most interesting object in neuroscience. Recently, researchers from Harvard University and Google released a 1.4-petabyte dataset of a small sample of the human cerebral cortex (a surface layer of the brain, responsible for higher-level cognitive functions). The sample has been imaged at 4nm-resolution using electron […]
June 5, 2021

Case Western Reserve-led research team aims to determine which diabetic individuals can successfully donate corneas for transplant (and which should not)

About a third of the corneal transplant surgeries in the United States involve people with diabetes who donate their corneas after death. The number of corneal transplants has grown over the last decade, but through continuous research, the medical community has learned that not all corneal tissue from diabetics may […]
June 5, 2021

VUMC team discovers new genetic disease

Researchers at Vanderbilt University Medical Center have discovered a new genetic disease that causes a severe form of neurogenic orthostatic hypotension, a rapid drop in blood pressure upon standing that can cause fainting. The rare condition, which they named familial autonomic ganglionopathy, is caused by variations in the CHRNA3 gene, […]
June 5, 2021

Studying guppies, researchers find ADHD drugs can affect later generations

By studying guppies, scientists at the University of Toronto and Florida State University found that behaviours affected by methylphenidate hydrochloride (MPH) – the active ingredient in stimulants such as Ritalin and Concerta used to treat ADHD – can be passed along to several generations of descendants. “We exposed male and female Trinidadian […]
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