March 30, 2022

A Discussion of Applying Partial Reprogramming to Senescent Cells In Vivo

Partial reprogramming exposes senescent cells to the Yamanaka factors for long enough to reset their epigenetic patterns to those of a youthful cell, but not so long as to force a change of state into induced pluripotent stem cells. This is an active area of research, not yet an exact […]
March 30, 2022

A CNIC study highlights the risks of mitochondrial therapeutic interventions

The mixing of mitochondrial DNAs (mtDNAs) of two distinct origins can have damaging medium- and long-term effects, according to the results of a new study published in Circulatio. Research carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has demonstrated that mixing mitochondrial DNAs (mtDNAs) of different origins can […]
March 29, 2022

Damage-Associated Molecular Patterns (DAMPs) in the Aging Retina

The immune system reacts to damaged and dying cells, as well as their debris. As the level of tissue damage rises with age, this pattern recognition contributes to increasing levels of chronic inflammation. That in turn causes further harm, changing cell behavior for the worse, degrading tissue structure and function. […]
March 29, 2022

COVID-19: "Reactive" Vaccination, Effective in Case of High Viral Circulation?

Although the majority of its population is fully vaccinated, the virus continues to actively circulate in France. As health restrictions are being lifted, fears of a resurgence of the epidemic and of the emergence of new more contagious variants are leading scientists to consider new strategies to continue to promote […]
March 28, 2022

How flossing and brushing may be good for your lungs

From chewing sticks to using twigs, hog bristles and horsehair, people have been polishing their pearly whites for millennia. Now EU scientists are investigating whether good oral hygiene can also protect us from chronic lung diseases. They’re also checking what our saliva says about our overall health. Did you ever […]
March 28, 2022

Elderly care? Bring in the robots!

Robots have come a long way. For years they have been supporting human activity – enabling exploration in dangerous and unreachable environments like out in space and deep in the oceans. A new generation of robots are being designed to stay closer to home – caring for ageing adults and […]