General

Are there many strategies that can reverse cellular senescence? There are certainly strategies that can lower levels of cellular senescence over time, both in cell cultures and in living animals, but very few are actually reprogramming senescent cells into normal cells. It isn't clear that this reversal of the senescent […]

Acute Lymphoblastic Leukemia (ALL), a cancer involving white blood cells known as lymphocytes, is the most common childhood cancer, representing 25% of all cancer diagnoses. It’s also one of the leading causes of childhood cancer deaths. While cure rates have improved thanks to chemotherapy, the cancer treatments are toxic. Survivors […]

Brain metastasis occurs when cancer in one part of the body spreads to the brain. The lifetime incidence of such metastatic brain tumors in cancer patients is between 20%-45%, research shows. A new study from USC Norris Comprehensive Cancer Center, part of Keck Medicine of USC, suggests that the region cancer spreads to in […]

In the fight against diseases like ALS, USC Viterbi biomedical engineering researchers have created a powerful lab model to better see how our muscles and neurons connect. Neuromuscular diseases are debilitating and mostly incurable, affecting 160 out of every 100,000 people worldwide. Disorders such as ALS and multiple sclerosis impact […]

QUT-led research on the interaction between prostate cancer cells and the tumour microenvironment has shed more light on the propensity of some types of prostate cancer to metastasize to bone more readily than other types. Microenvironment surrounding primary prostate cancer tumour driver of growth and spread Study compared microenvironment influence […]

New research from Trinity College and University of Edinburgh has examined the association between vitamin D and COVID-19, and found that ambient ultraviolet B (UVB) radiation (which is key for vitamin D production in the skin) at an individual’s place of residence in the weeks before COVID-19 infection, was strongly […]

Children who eat a better diet, packed with fruit and vegetables, have better mental wellbeing – according to new research from the University of East Anglia Health and Social Care Partners. A new study published is the first to investigate the association between fruit and vegetable intakes, breakfast and lunch […]

Researchers at the University of East Anglia and James Paget University Hospital are launching a new project to see whether Vitamin A could help people regain their sense of smell after viral infections including Covid-19. Smell loss is a common symptom of Covid-19, but even before Covid, many viruses had […]

USC Viterbi Ph.D. student researchers have found a new way to enhance the cancer-killing properties of CAR T-cell therapies, to make them more effective in fighting tumors. Cancer is the second leading cause of death in the United States. But in recent years, a revolutionary therapy has brought new hope […]

People love stories. We find it easier to remember events when they are part of an overarching narrative. But in real life, the chapters of a story don’t follow smoothly one from another. Other things happen in between. A new brain imaging study from the Center for Neuroscience at the […]

A new study provides insights into the cellular mechanisms involved in Christianson syndrome, an X-linked genetic disorder characterized by delayed development, cognitive disability and epileptic seizures as well as difficulties with speech, balance and mobility. This research, published in the Journal of Neuroscience, demonstrates how a cellular process known as […]

As SARS-CoV-2 continues to evolve, new variants are expected to arise that may have an increased ability to infect their hosts and evade the hosts' immune systems. The first key step in infection is when the virus’ spike protein binds to the ACE2 receptor on human cells. Researchers at Penn […]

Describing a previously unknown genetic condition that affects children, researchers at University of California San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine say they also found a potential method to prevent the gene mutation by administering a drug during pregnancy. The findings were published in the […]

Researchers at the University of Southampton have invented a new way to generate human cartilage tissue from stem cells. The technique could pave the way for the development of a much-needed new treatment for people with cartilage damage. Cartilage acts as a shock absorber in joints, but it is susceptible […]

For the first time, researchers have identified key molecules within the immune system that may help fight the inflammation that drives chronic diseases including cancers, sepsis and brain disease. The University of Queensland collaborated with the Indian Institute of Technology, Kanpur on the study. UQ Professor Trent Woodruff said the research investigated […]

The processes of autophagy act to remove damaged molecular machinery and structures in the cell. Autophagy becomes dysfunctional with age, however. This is likely downstream of underlying causes of aging that cause changes in gene expression that degrade the function of autophagic processes in one way or another. For example […]