Related Science News

February 12, 2021

Study: New Prostate Cancer Test Could Avoid Unnecessary Biopsies

A urine test based on University of Michigan Rogel Cancer Center research could have avoided one-third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. The findings appear in the issue of the Journal of Urology. […]
February 12, 2021

Stem Cell Study Illuminates the Cause of a Devastating Inherited Heart Disorder

Scientists in the Perelman School of Medicine at the University of Pennsylvania have uncovered the molecular causes of a congenital form of dilated cardiomyopathy (DCM), an often-fatal heart disorder. This inherited form of DCM — which affects at least several thousand people in the United States at any one time […]
February 12, 2021

Simple urine test can detect womb cancer

A simple non-invasive test can accurately detect womb cancer according to a proof of concept study by University of Manchester and Manchester University NHS Foundation Trust (MFT) scientists. The non-invasive test, which detects cancer by looking at urine or vaginal sample with a microscope, could have a major benefit for patients if […]
February 12, 2021

Gene variants increase risk of Addison’s disease

Variants of nine genes increase the risk of developing Addison’s disease, a rare disease in which the immune system attacks the adrenal glands. That is according to the largest genetic study to date on patients with Addison’s disease. The findings help increase knowledge about what causes the disease. The study […]
February 12, 2021

Aberrant splicing in neuroblastoma generates RNA-fusion transcripts and provides vulnerability to spliceosome inhibitors

Neuroblastoma arises within the sympathetic nervous system and is the most frequent extracranial solid childhood cancer, exhibiting a high degree of clinical heterogeneity ranging from spontaneous regression to fatal progression despite intense clinical intervention. Despite extensive sequencing efforts, the number of identified recurrent mutations remain low in pediatric neuroblastoma. Researchers […]
February 12, 2021

Improving Crohn’s Disease Evaluations in Kids

In people with Crohn’s disease, a chronic inflammatory bowel condition, symptoms or how they feel may not line up with actual inflammation in their gut. This mismatch creates challenges for accurately measuring how well a treatment is truly working, especially for children. Currently, many gastroenterologists use symptoms and blood tests […]
February 12, 2021

Research paper reveals new drug as ‘gamechanger’ in treatment for obesity

A research paper published in the New England Journal of Medicine has revealed that a new anti-obesity medication is almost twice as effective in helping people lose weight than other current weight loss drugs. Professor John Wilding, who leads clinical research into obesity, diabetes and endocrinology at the University of […]
February 12, 2021

Researchers identify drugs with potential to stop plaque buildup in arteries

Glycomics researchers at the University of Alberta and CHU Sainte-Justine have reported a discovery that could lead to new treatments for cardiovascular disease. The researchers identified a new mechanism responsible for the buildup of plaque on artery walls, a process known as atherosclerosis. This plaque, made up of fats, cholesterol […]
February 12, 2021

Molecular Details Reveal New Clues about Common Brain Tumor

Genetics and multi-omic information could one day inform treatments for glioblastoma. The largest and most detailed molecular analysis yet of an aggressive brain cancer, called glioblastoma, reveals fundamental details that drive its growth. The work, led by a team of scientists from the U.S. Department of Energy’s (DOE) Pacific Northwest […]
February 11, 2021

Shall we dance?

Dance is considered as one of the art forms. Regardless of whether we do it professionally or as a hobby, it gives us great pleasure, relaxes, and allows us to break away from the prose of life. Thus, dance can be beneficial for our mind, memory, stimulation of the nerve […]
February 10, 2021

Nanothermometry to improve anticancer strategies

IMDEA Nanociencia researchers measure the nanoscale heating of gold-based nanoparticles and find high temperature variations within a nanoscopic volume. In hyperthermia treatments, the temperature is raised above physiological levels to induce the death of cancerous cells. The local application of hyperthermia is key for a successful treatment and to reduce […]
February 10, 2021

A ‘skeletal age’ calculator to predict bone fracture risk

Researchers at the Garvan Institute of Medical Research have developed a computational model to calculate ‘skeletal age’, a personalised estimate of an individual’s risk of bone fracture and premature death. The skeletal age calculator, which will be accessible to doctors and health professionals, aims to better identify those at risk […]
February 10, 2021

Radiation Vulnerability

Exposure to radiation can wreak indiscriminate havoc on cells, tissues, and organs. Curiously, however, some tissues are more vulnerable to radiation damage than others. Scientists have known these differences involve the protein p53, a well-studied tumour-suppressor protein that initiates a cell’s auto-destruct programs. Yet, levels of this sentinel protein are […]
February 10, 2021

Distinctness of mental disorders traced to differences in gene readouts

NIH researchers take “deep dive” into brain’s transcriptome. A new study suggests that differences in the expression of gene transcripts – readouts copied from DNA that help maintain and build our cells – may hold the key to understanding how mental disorders with shared genetic risk factors result in different patterns […]
February 10, 2021

How having a disability can spur the brain to develop new abilities

Professor Kimitaka Nakazawa, a specialist in neurorehabilitation, first had the opportunity to study the brain activity of a Paralympic gold medalist in January 2016, when he visited a university pool in the United States as part of an NHK television program called “Chojin-tachi no Paralympic” [The superhuman Paralympians]. He was […]
February 10, 2021

New CRISPR tech targets human genome’s complex code

Rice University’s programmable CRISPR/Cas9-based kinase offers insights into, control over regulatory histone proteins. Finding a needle in a haystack is hard enough. But try finding a specific molecule on the needle. Rice University researchers have achieved something of the sort with a new genome-editing tool that targets the supporting players […]
February 10, 2021

Frail people with COVID-19 are three times more likely to die from the infection

COVID-19 is a very dangerous disease, but risks are not equal to everyone. Older people are facing higher risks of complications from COVID-19 and should be protected more. Now scientists at the University of Birmingham have shown that frail individuals are much more likely to die from COVID-19. Frailty is […]
February 9, 2021

Machine learning can help doctors diagnose Parkinson’s disease by looking at patients’ movements

Scientists from Skoltech and A.I. Burnazyan Federal Medical and Biophysical Center have designed and developed a second opinion system, based on AI-assisted video analysis, which can help medical professionals to objectively assess patients with Parkinson’s disease (PD) even at an early stage. This approach can help avoid misdiagnosing this disease, […]
February 9, 2021

What happens in the mouth … doesn’t stay in the mouth

We know that what happens in the mouth doesn’t stay in the mouth – but the oral cavity’s connection to the rest of the body goes way beyond chewing, swallowing and digestion. The healthy human oral microbiome consists of not just clean teeth and firm gums, but also energy-efficient bacteria […]
February 9, 2021

Clinical trials begin to investigate treatment for diabetic eye disease

A new approach to treating one of the leading causes of blindness among patients with diabetes is being tested in clinical trials which begin this month. The trial involves 48 patient volunteers with diabetic macular oedema (DMO), a disease where blood vessels leak fluid into the retina. It is the […]
February 9, 2021

RNA molecules are masters of their own destinies

At any moment in the human body, in about 30 trillion cells, DNA is being “read” into molecules of messenger RNA, or mRNA, the intermediary step between DNA and proteins, in a process called transcription. Scientists have a good idea of how transcription gets started. Proteins called RNA polymerases are […]
February 9, 2021

Hearing Acrobatics

Dynamic, delicate connection between protein filaments enables hearing. The sense of hearing is, quite literally, a molecular tightrope act. Turns out, it involves acrobatics as well. In a paper published in Nature Communications, researchers at Harvard Medical School and Boston Children’s Hospital show that a dynamic and delicate connection between two […]
February 9, 2021

What rules govern the structure of membraneless organelles?

In cells, numerous important biochemical functions take place within spherical chambers made from proteins and RNA. These compartments are akin to specialized rooms inside a house, but their architecture is radically different: They don’t have walls. Instead, they take the form of liquid droplets that don’t have a membrane, forming […]
February 9, 2021

Dietary Adherence and the Fight Against Obesity

While eating less and moving more are the basics of weight control and obesity treatment, finding ways to help people adhere to a weight-loss regimen is more complicated. Understanding what features make a diet easier or more challenging to follow can help optimize and tailor dietary approaches for obesity treatment. […]
February 9, 2021

Study finds high potential for developing dementia for agricultural workers

A University of Iowa study finds people who work long-term in the agricultural industry have 46% greater odds of developing dementia than those in other fields. Professor Kanika Arora in the U-I College of Public Health, says hearing impairment, depression and isolation can all be linked to dementia and to […]
February 8, 2021

Researchers find link between children’s time perception and risk for developmental coordination disorder

Neuroscientists at McMaster University have found a link between children who are at risk for developmental coordination disorder (DCD), a common condition that can cause clumsiness, and difficulties with time perception such as interpreting changes in rhythmic beats. Accurate time perception is crucial for basic skills such as walking and […]
February 8, 2021

Artificial Intelligence can help diagnosing depression and psychosis

Artificial intelligence is going to become a great diagnostics tool in medicine. It can notice details in images that go unnoticed for a human eye. However, up until now it was almost impossible to imagine AI being used to diagnose mental conditions. Now scientists at the University of Birmingham have […]