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Klotho is one of the few well-established longevity-associated genes that works in both directions in animal models: less klotho shortens life span, while more klotho extends life. Klotho also improves cognitive function. The mechanisms by which klotho produces these outcomes remain poorly understood: there is the usual grab-bag of identified […]

Loss of muscle mass and strength in astronauts remains an issue for space exploration. Caenorhabditis elegans (C. elegans), a nematode species that is 1 mm long, shares common traits with humans and these worms are a good, cost-effective model for studying the effects of spaceflight on muscle. A NASA-funded research team […]