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When we are exposed to a pathogen, the immune system’s B cells swarm to our lymph nodes, spleens, and tonsils. There, those cells mutate in germinal centers—microscopic boot camps that rush the B cells through volleys of mutations to produce the most potent antibodies for neutralizing the infectious agent. As […]

Developing drugs to combat tuberculosis, or TB, can be frustrating business. A gene essential to the bacteria’s lifecycle is discovered, scientists rush to develop drugs that inhibit the target, and then—disappointment. Volleys of compounds hurled at the essential gene target have little impact on microbial growth. The bacteria live on. […]

Unique development is biocompatible and does not require electricity, wires, or batteries. Tel Aviv University (TAU) researchers have developed a technology that involves a tiny sensor implanted in the nerve of an injured limb and is connected directly to a healthy nerve. Each time the limb touches an object, the sensor […]

The body’s so-called good cholesterol maybe even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury. This HDL protects the liver by blocking inflammatory signals […]

According to research supported by NIH's National Eye Institute, a form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma. The findings suggest a way forward for developing neuroprotective therapies for glaucoma, a leading cause of visual impairment and blindness. The report was published […]

Elevated levels of three specific circulating proteins are associated with protection against kidney failure in diabetes, according to new research from Harvard Medical School researchers at Joslin Diabetes Center published in Science Translational Medicine. “As well as acting as biomarkers for advancing kidney disease risk in diabetes, the proteins may also […]

Over the last decade, investigators at Beth Israel Deaconess Medical Center have been at the forefront of the effort to identify the small population of neurons deep within the brain that causes hunger. But precisely how these cells and the unpleasant feeling of hunger they cause actually drive an animal to […]

No amount of lead in drinking water is safe for people with kidney disease, study shows Despite advances in reducing the amount of lead in drinking water, low levels of contamination remain widespread throughout the United States. This may be especially dangerous for the 30 to 40 million Americans living […]

By implementing a long-term, prospective approach to the development of celiac disease, a collaborative group of researchers has identified substantial microbial changes in the intestines of at-risk infants before disease onset. Using advanced genomic sequencing techniques, MassGeneral Hospital for Children (MGHfC) researchers, along with colleagues from institutions in Italy and […]

T-cells play a crucial role in how the body responds to infection – and have become a key focus for scientists during the COVID-19 pandemic as they hunt for ways to kill the SARS-CoV-2 virus. In this study, the researchers uncovered more about how these cells and their receptors work, […]

The six-month campaign will target parts of South Wales with poor cancer survival rates and highlight six possible symptoms, including unexplained weight loss, loss of appetite, nausea, persistent fatigue, abdominal pain and “not feeling yourself”. The initiative aims to encourage adults in the Cwm Taf Morgannwg University Health Board area […]

A new study, led by University of Minnesota Twin Cities engineering researchers, shows that the stiffness of protein fibers in tissues, like collagen, are a key component in controlling the movement of cells. The groundbreaking discovery provides the first proof of a theory from the early 1980s and could have […]