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Muscle aches and pains, whether from stretching, strenuous exercise or just normal wear and tear, can put a crimp in your day, a limp in your step and be an actual pain in the neck. But no matter the severity, stem cells in the skeletal muscles called satellite cells play […]

Since the 1960s, researchers have been interested in the possibility of treating type 1 diabetes by transplanting islet cells — the pancreatic cells that are responsible for producing insulin when blood glucose concentration increases. Implementing this approach has proven challenging, however. One obstacle is that once the islets are transplanted, […]

Study examines how early embryonic development can go awry. A new study in the journal Nature Cell Biology has uncovered information about a key stage that human embryonic cells must pass through just before an embryo implants. The research, led by UCLA biologist Amander Clark, could help explain certain causes […]

An Arizona startup is hoping its unique compounds will lead to treatments to halt or slow the progression of a devastating neurodegenerative disease that affects nearly 6 million Americans. Iluminos Therapeutics has licensed compounds created at the University of Arizona that have the potential to treat neurodegenerative disease, in particular […]

Breast cancer is the most common form of cancer in women and the most common cause of death in middle-aged women in Sweden. Triple-negative breast cancer (TNBC) is an aggressive and difficult to treat form of the disease that makes up about 15 per cent of all breast cancer cases. […]

Age-related macular degeneration, a disease that slowly degrades light-sensitive cells in the retina, is the leading cause of vision loss and blindness among people 65 and older, according to the Centers for Disease Control and Prevention. Doctors can’t prevent such loss of sight – but a system that replaces light-sensitive […]

Mastitis is the most expensive disease in the dairy industry. Each clinical case can cost a dairy farmer more than $400 and damages both the cow’s future output as well as her comfort. Bovine mastitis is typically treated with antibiotics, but with the potential threat of antimicrobial resistance and the […]

At Penn, collaboration is as ingrained in the culture as innovation. And, it turns out, some teams end up having quite the crew. One specific group—working to detect early stage ovarian cancer—maintains experts spanning obstetrics and gynecology, chemistry, physics, and veterinary care. It also includes human’s best furry friends: dogs. As […]

Regular physical activity may help older women increase their mobility, but muscle strength and endurance are likely to succumb to the effects of frailty if they haven’t also been doing resistance training. That is according to the findings of a cross-sectional study led by the University at Buffalo and published […]

Using a homemade, high-tech microscope, scientists at the University of Virginia School of Medicine have revealed how a cancer-causing virus anchors itself to our DNA. That discovery could pave the way for doctors to cure previously incurable diseases by flushing out viruses, including HPV and Epstein-Barr, that now permanently embed […]

A remote command could one day send immune cells on a rampage against a malignant tumor. The ability to mobilize, from outside the body, targeted cancer immunotherapy inside the body has taken a step closer to becoming reality. Bioengineers at the Georgia Institute of Technology have installed a heat-sensitive switch […]

Research led at the Yale School of Public Health have found that the majority of published papers analyzing the cost-effectiveness of a widely used test for breast cancer used a study design that can increase bias. Oncotype DX, a gene-expression profiling test, is used in clinical care to guide chemotherapy […]

But platelets also release so-called growth factors that help repair soft tissues – blood vessels, skin, muscle, tendons – and recruit other cells to speed the healing process. Those capabilities have made platelet-rich plasma an emerging treatment option for certain joint injuries and post-operative therapies. Now researchers from the University […]

Exposure to a toxin primarily found in sheep could be linked to the development of multiple sclerosis (MS) in humans, new research suggests. Carried out by the University of Exeter and MS Sciences Ltd., the study has found that people with MS are more likely than other people to have […]

While older drivers as a group have a relatively high rate of car crashes, few validated tools exist to evaluate an individual’s crash risk and to help older adults make the life-altering decision to give up their car keys. Aiming to better understand how adults’ crash risk changes over time, […]

A rear-ender in which the driver’s head slams against the steering wheel or a helmet-to-helmet tussle with an opponent on the football field may increase one’s risk for Parkinson’s disease if concussion results, say researchers from UCSF and the San Francisco Veterans Affairs Medical Center. In their study, which publishes […]

A new scientific study shows that exposure of preschool children to bright electric light in the evening suppresses melatonin production almost completely, an important addition to the growing body of research in this area. Melatonin suppression is a marker of disruption of our circadian rhythms. Ten kids, ages 3 to 5, were […]

Scientists have identified the molecular mechanism that leads to the death of neurons in amyotrophic lateral sclerosis (also known as ALS or motor neurone disease) and a common form of frontotemporal dementia. Writing in Cell, the researchers from the University of Cambridge and University of Toronto also identify potential therapeutic targets for these currently incurable […]

Back in 2013, researchers achieved human brain organoids for the first time, which they had eventually managed to induce to form structures like those seen in the brains of foetuses. The problem with the brainy organoids is their short life-span. “In our hands, the organoids stop growing around five weeks,” […]

Infection with Epstein-Barr virus (EBV), the cause of infectious mononucleosis, has been associated with subsequent development of systemic lupus erythematosus and other chronic autoimmune illnesses, but the mechanisms behind this association have been unclear. Now, a novel computational method shows that a viral protein found in EBV-infected human cells may […]

Most of the roughly 15.5 million cancer survivors in the U.S. receive chemotherapy, and roughly 65 percent develop some degree of the chemotherapy-induced nerve damage known as peripheral neuropathy. Peripheral neuropathy simply means nerves outside of the brain and spinal cord are affected, and symptoms include numbness and tingling in […]

The method involves the use of a new type of a nanotube – a tiny tube used in many applications, including drug delivery. This new type, designed and created by Dr Ben Newland at Cardiff University, is made from a non-toxic polymer called poly(ethylene glycol).  Unlike current nanotubes, which can cause […]

New research, published in Biological Reviews and conducted by researchers from the University of Liverpool and Escola Superior de Ciências da Saúde (Brasília, Brazil) has found some type of cancers unique to humans may be a result of evolutionary accidents. Cancer is a major cause of death worldwide. But humans are not […]

All of the body’s organs contain macrophages, which, as part of the immune system, consume bacteria and other foreign bodies. However, macrophages are also specialised according to the organ in which they operate; in the brain they are known as microglia, and researchers believe that this specialisation is controlled by […]

The small, pilot study aims to recruit seven people to find out if the bone marrow stem cell mobilising drug, granulocyte-colony stimulating factor (GCSF), could improve blood markers and potentially treat the condition. GCSF, which is commonly used in diseases related to the blood, as well as in healthy people […]

New research published in The Lancet and co-authored by Professor Lucilla Poston CBE, shows that the diet and lifestyle of both parents before conception plays a key role in the long-term health of their children. In a series of papers Professor Poston, Head of King’s School of Life Course Sciences, and colleagues from […]

Older adults who take a novel antioxidant that specifically targets cellular powerhouses, or mitochondria, see aging of their blood vessels reverse by the equivalent of 15 to 20 years within six weeks, according to new CU Boulder research. The study, published this week in the American Heart Association journal Hypertension, […]

Cancer is not as scary as it used to be. Of course, it is a terrible condition which causes a lot of deaths worldwide every year. But nowadays we have novel therapies to combat cancer, even though sometimes it is difficult to say what is and what isn‘t working. Now […]

Non-Hodgkin lymphoma, a cancer that is diagnosed in the U.S. more than 70,000 times annually, arises from overly proliferating immune cells within the body’s lymph nodes, which are connected to a network of lymph vessels through which lymphatic fluid flows. The most common type of lymphoma is diffuse large B-cell […]

Despite the great successes of targeted cancer drugs and the promise of novel immunotherapies, the vast majority of people diagnosed with cancer are still first treated with chemotherapy. Now a new study by UCSF researchers using techniques drawn from computational biology could make it much easier for physicians to use […]