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Patients with Type 2 diabetes who were prescribed SGLT2 inhibitors lost more weight than patients who received GLP-1 receptor agonists, according to a University at Buffalo-led study. The research, which sought to evaluate the difference in weight loss caused by the antidiabetic medications — both of which work to control […]

Genetic technique edits every chloroplast in a plant, but does not change nuclear DNA of offspring. Breeding better crops through genetic engineering have been possible for decades, but the use of genetically modified plants has been limited by technical challenges and popular controversies. A new approach potentially solves both of […]

A new technique called sci-Space, combined with data from other technologies could lead to four-dimensional atlases of gene expression across diverse cells during the embryonic development of mammals. Such atlases would map how the gene transcripts in individual cells reflect the passage of time, cell lineages, cell migration, and location […]

The accumulation of senescent cells is an important contributing cause of degenerative aging. This is not a recent discovery, enough was known 20 years ago for the first SENS rejuvenation research proposals to prominently feature removal of senescent cells as an approach to treating aging as a medical condition, but […]

The Forever Healthy Foundation has been building a database of materials covering presently available options for the treatment of aging, all of which have little available data in comparison to more established areas of medicine. The bias in these materials is towards a very conservative viewpoint, appropriate for physicians, so […]

Immunotherapy based on supercharging the immune system’s natural killer cells has been effective in treating patients with recurrent leukemia and other difficult to treat blood cancers. Now, researchers at Washington University School of Medicine in St. Louis have shown in preclinical studies conducted in mice and human cells that this […]

The effect and selectivity of dietary fibers on intestinal bacteria is now demonstrated. In a series of controlled trials, researchers from DTU and Washington University School of Medicine, St. Louis (USA), show that plant-based fibers affect the microbiome of mice that host a human microbiota and as well as that […]

Researchers have found that eating disorder behaviors, such as binge-eating, alter the brain’s reward response process and food intake control circuitry, which can reinforce these behaviors. Understanding how eating disorder behaviors and neurobiology interact can shed light on why these disorders often become chronic and could aid in the future […]

A new study finds that exposure to e-cigarette vapor leads to higher levels of the coronavirus receptor ACE-2 in lungs of mice, with nicotine enhancing that increase in male mice. The use of e-cigarettes, or vaping, causes serious damage to the lungs. After the novel coronavirus responsible for the respiratory […]

The immune system is complex and ages in complex ways, pressed by the lifetime burden of infection and rising levels of molecular damage that trigger many of the same innate immune responses as are produced by invading pathogens. The common innate immune cells known as macrophages play many roles in […]

A number of papers in recent years have suggested there to be a link between gum disease (periodontitis) and neurodegeneration. Similarly to the correlation with heart disease, it is thought that the underlying mechanism is raised chronic inflammation deriving from toxins released into the bloodstream by the bacteria that cause […]

A group of scientists led by researchers at the University of North Carolina at Chapel Hill, Weill Cornell Medicine and NewYork-Presbyterian reported that the Moderna mRNA vaccine and a protein-based vaccine candidate elicited durable neutralizing antibody responses to SARS-CoV-2 in preclinical research. There were no adverse effects. The research, published […]