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It is well known that gene expression becomes disarrayed in cells in old tissues. Mechanisms controlling the structure of nuclear DNA become dysfunctional, and that can unleash all sorts of errant protein production by allowing the machinery of gene expression to reach sections of the genome that are normally folded […]

Salk researchers pinpoint a sound-sensitive mammalian protein that lets them activate brain, heart or other cells with ultrasound. Salk scientists have engineered mammalian cells to be activated using ultrasound. The method, which the team used to activate human cells in a dish and brain cells inside living mice, paves the […]

Salk researchers treated mice with anti-aging regimen beginning in middle age and found no increase in cancer or other health problems later on. Age may be just a number, but it’s a number that often carries unwanted side effects, from brittle bones and weaker muscles to increased risks of cardiovascular […]

Researchers at Osaka University show that intercellular communication via extracellular vesicles from bone-making osteoblasts is a key factor for the switch from bone formation to resorption through a microRNA-mediated mechanism. Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each […]