A technology of cell cryopreservation allows for application of healthy autologous immune cells when the protective abilities of the body are reduced as a consequence of aging or disease.
Cryogenic storage of immune cells
Aging of the immune system inevitably results in weakening both protective and regenerative capabilities of the body. The T-cell-mediated immunity especially suffers in older people. “Old” T lymphocytes exhibit a decreased ability to recognize different pathogens and to support regenerative processes. In turn, the B-cell-mediated immunity suffers from functional T-cell abnormalities. Non-specific anti-infective protection also becomes much weaker, due to the decrease in metabolic activity in phagocyte cells. Hence, the aging of the immune system makes the body defenseless against infectious, cancer and autoimmune diseases.
The transfusion of functionally active healthy immune cells is the only opportunity to cardinally improve the immune functions in the elderly. The technology of cell cryopreservation allows for using autologous healthy immune cells at that time, when protective resources of the body reduced as a result of aging or disease. The availability of such cells for medical use is a peculiar biological insurance that expands applications of the various immunotherapeutic technologies, including those aimed at achieving active longevity.